Results 61 to 70 of about 4,234 (257)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Multi-User Detection for Group Orthogonal Multi-Carrier Code Division Multiple Access System in Frequency Selective Rayleigh Fading Channel

Journal of Engineering and Sustainable Development, 2008
Code Division Multiple Access (CDMA) suffers from multi-user interference (MUI), and intersymbol interference (ISI) under frequency selective multi-path fading channels. Orthogonal Frequency Division Multiple access (OFDM) is MUI free but achieves lower
Maha George Zia, Harith Akram Nassir
doaj  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

ADAPTIVE PATH SELECTIVE MULTIPATH-DECORRELATING RECEIVER FOR SYNCHRONOUS CDMA FREQUENCY-SELECTIVE FADING CHANNELS

Electrica, 2019
In the conventional multipath-decorrelating receiver, the complexity and noise enhancement increase with the number of resolvable paths. In this paper, we propose a scheme that adaptively selects a subset of the paths reducing both system complexity and ...
Ali Hakan ULUSOY, Hasan AMCA, Kadri HACIOĞLU, Ahmet RIZANER   +3 more
doaj   +2 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Advantages of multiple estimation in the frequency-selective block fading MIMO environments

Majlesi Journal of Electrical Engineering
The performance of the multiple-estimation (ME) is examined in multiple-input multiple-output (MIMO) frequency-selective fading channels. The least squares (LS) technique, the shifted scaled least squares (SSLS) estimator, and the minimum mean square ...
OICC Press Authors
doaj  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Doppler Spread Estimation in MIMO Frequency-Selective Fading Channels

IEEE Transactions on Wireless Communications, 2018
One of the main challenges in high-speed mobile communications is the presence of large Doppler spreads. Thus, accurate estimation of maximum Doppler spread (MDS) plays an important role in improving the performance of the communication link. In this paper, we derive the data-aided (DA) and non-data-aided (NDA) Cramer-Rao lower bounds (CRLBs) and ...
Mostafa Mohammadkarimi, Ebrahim Karami, Octavia A. Dobre, Moe Z. Win   +3 more
openaire   +5 more sources

Slantlet based Polynomial Cancellation Coding OFDM

Journal of Engineering and Sustainable Development, 2008
In this paper a new technique is proposed to improve the performance of OFDM. This technique uses the slantlet transform (SLT) instead of fast Fourier transform (FFT) to reduce the level of interference. This also will remove the need for guard interval
Hikmat N. Abdullah, Safa’a A. Ali
doaj  

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source