Results 161 to 170 of about 737,986 (350)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A compact frequency-selective absorber with optical transparency

open access: yesMaterials Research Express
This article proposes a new method for designing an optical transparent frequency-selective surface absorber using indium tin oxide (ITO) conductive film with different sheet resistances.
Kewen Deng   +4 more
doaj   +1 more source

Frequency selective absorption using lumped element frequency selective surfaces

open access: yesElectronics Letters, 2003
A three-layer frequency selective surface (FSS) filter is presented that over a narrow frequency band simultaneously attenuates the microwave signal transmitted through and reflected from the filter. This is achieved using a lumped element resistive FSS in between a conventional FSS and a lumped element capacitive FSS.
openaire   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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