Results 121 to 130 of about 6,614,970 (338)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Design of Liquid Based Frequency Selective Surfaces Operating as Absorbers

Advances in Electrical and Computer Engineering
Liquid-based absorbers using frequency selective surfaces (FSSs) rely on 2D periodic lattices. Each unit cell contains one or more resonators filled with liquids, which dissipate electromagnetic energy.
DE SABATA, A., SILAGHI, A., IONICA, C., PACURAR, O.   +3 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Multiband frequency selective surfaces with a modified multifractal cantor geometry

Journal of Microwaves, Optoelectronics and Electromagnetic Applications
Self-affine property of a modified multifractal Cantor geometry is exploited to design frequency selective surfaces (FSS) with multiband response. The main advantage of the proposed structure is to design multiband FSS with multiple frequency ratios ...
Érico Cadineli Braz, Antonio Luiz Pereira de Siqueira Campos   +1 more
doaj   +1 more source

Angle-selective surface based on multi-layered frequency-selective surfaces

, 2022
Angle-selective surfaces (ASSs) can provide angular selectivity for the incident plane electromagnetic waves. One way to realize such angular selectivity is to employ multilayered frequency-selective surfaces (FSSs).
Hong, Yujing
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Cascaded Frequency Selective Surfaces with Matryoshka Geometry for Ultra-Wideband Bandwidth

Applied Sciences
The purpose of this paper is to present cascaded frequency selective surfaces (FSSs) with matryoshka geometry to increase the effective bandwidth.
Ianes Coutinho, Francisco Madeiro, Wamberto Queiroz   +2 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Active Multifunctional Frequency Selective Surfaces: An Insight Into Design, Behavior Analysis, and Applications

IEEE Access
This investigation provides a critical review of the design methodologies for multifunctional active frequency selective surfaces (MAFSSs) and reconfigurable frequency selective surfaces (RFSSs), collectively referred to as active multifunctional ...
Harienthiran Maheswaran, Gulam Nabi Alsath Mohammed, Geethanjali Govindarajan, Malathi Kanagasabai, Kirubaveni Savarimuthu, Sandeep Kumar Palaniswamy, Sachin Kumar, Bhawna Goyal, Mousa I. Hussein   +8 more
doaj   +1 more source