Results 121 to 130 of about 311,651 (309)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Burnout syndrome and fatigue among healthcare workers at the Neurology Department of University Hospital of Split.

, 2023
Cilj istraživanja: Cilj istraživanja bio je istražit učestalost sindroma sagorijevanja na poslu i umora u zdravstvenih djelatnika na Klinici za neurologiju KBC Split te moguću povezanost sindroma sagorijevanja na poslu i umora.
Cvitković, Luka
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Pectoral Fin Structural Design and Experiments on Robotic Cow-Nosed Ray with Backward Swimming Performance

水下无人系统学报
Robotic fish with pectoral fin swing have many outstanding features, especially forward swimming stability, but the research on their backward swimming performance is insufficient.
Bo LI, Yingming YU, Yonghui CAO, Yiwei HAO, Guang PAN, Yong CAO   +5 more
doaj   +1 more source

The profile of young volounteers in Split

, 2017
U ovome radu prikazani su i interpretirani rezultati istraživanja provedenog na mladim volonterima i volonterkama grada Splita. Cilj rada bio je ispitati njihov profil, te uočiti načine na koje oni upravljaju s individualnim, kulturnim i društvenim ...
Maglov, Ana
core  

The impact of the COVID pandemic on the frequency of clinical isolates of Acinetobacter baumannii at the University Hospital of Split

, 2022
Cilj istraživanja: Odrediti učestalost kliničkih izolata Acinetobacter baumannii u tromjesečnom razdoblju praćenja prije i tijekom COVID-19 pandemije u Republici Hrvatskoj te usporediti broj i osjetljivost kliničkih izolata A.
Grulović, Mia
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Split-ring resonator with interdigital Split electrodes as detector for liquid and ion chromatography

Sensing and Bio-Sensing Research
The analysis of food and drugs as well as the monitoring of chemical processes and bioreactors by high-performance liquid chromatography and ion chromatography requires universal, cost-effective, and sensitive detectors.
Kirsten J. Dehning, Moritz Hitzemann, Stefan Zimmermann   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source