Results 71 to 80 of about 6,200,319 (299)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Brownian motion-induced amplitude noise in vapor-cell frequency standards

open access: yesNew Journal of Physics, 2020
We demonstrate that the Brownian motion of alkali metal atoms in buffer gas gives rise to a significant source of frequency instability in vapor cell clocks.
S Micalizio   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Improving Microgrid Frequency Regulation Based on the Virtual Inertia Concept while Considering Communication System Delay

open access: yesEnergies, 2019
Frequency stability is an important issue for the operation of islanded microgrids. Since the upstream grid does not support the islanded microgrids, the power control and frequency regulation encounter serious problems.
Gholam Ali Alizadeh   +4 more
doaj   +1 more source

Joint Timekeeping of Navigation Satellite Constellation with Inter-Satellite Links

open access: yesSensors, 2020
As a system of ranging and positioning based on time transfer, the timekeeping ability of a navigation satellite constellation is a key factor for accurate positioning and timing services. As the timekeeping performances depend on the frequency stability
Leyuan Sun   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Comparative Analysis of Current Control Techniques to Support Virtual Inertia Applications

open access: yesApplied Sciences, 2018
The rapid transition towards an inverter-dominated power system has reduced the inertial response capability of modern power systems. As a solution, inverters are equipped with control strategies, which can emulate inertia by exchanging power with the ...
Ujjwol Tamrakar   +6 more
doaj   +1 more source

Short-Term Frequency Stability [PDF]

open access: yes, 1965
Panel discussion on frequency stability measurement ...

core  

0.1 Hz/Hz√ Frequency Stability in a Passive, Optical Fiber Frequency Reference

open access: yes, 2022
A digital interferometric fiber frequency reference is demonstrated with frequency stability of 0.1 Hz/√Hz above 100 Hz. The thermal stability is validated using an optical frequency comb, and key noise sources are identified and ...
Gray, Malcolm   +4 more
core   +1 more source

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