Results 41 to 50 of about 186,401 (311)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Chip Scale Atomic Resonator Frequency Stabilization System With Ultra-Low Power Consumption for Optoelectronic Oscillators

open access: yes, 2016
We present a long-term chip scale stabilization scheme for optoelectronic oscillators (OEOs) based on a rubidium coherent population trapping (CPT) atomic resonator.
Zhang, Yaolin   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Laser-frequency locking techniques for high-sensitivity strain measurements by high-birefringence fiber Bragg gratings and resonators [PDF]

open access: yes, 2007
A new approach to simultaneously interrogate orthogonal axes of single Fiber- Bragg-Gratings (FBGs) and FBG-FabryPerot resonator sensors fabricated in linearly highly birefringent (HiBi) fibre is presented.
Ferraro, P.   +13 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Steady-State Analysis of the Effects of Residual Amplitude Modulation of InP-Based Integrated Phase Modulators in Pound–Drever–Hall Frequency Stabilization

open access: yesIEEE Photonics Journal, 2019
Residual amplitude modulation of the phase modulator deployed in Pound–Drever–Hall frequency stabilization is an effect known to cause instabilities to the absolute wavelength of the stabilized laser. We present measurements and analysis of
Stefanos Andreou   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Head and body stabilization in blowflies walking on differently structured substrates

open access: yes, 2012
Kress D, Egelhaaf M. Head and body stabilization in blowflies walking on differently structured substrates. The Journal of experimental biology. 2012;215(9):1523-1532.Visually guided animals depend heavily on the quality of visual signals in order to ...
Kress, Daniel   +1 more
core   +1 more source

Effect of frequency stabilization on beam shift of total reflection prism laser gyro

open access: yes, 2022
For the phenomenon of degradation of the performance of total reflection prism laser gyro before and after reset jump, this paper investigates the effect of frequency stabilization on the beam shift of total reflection prism laser gyro using a matrix ...
Jiajun Ma   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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