Results 161 to 170 of about 554 (193)

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

Advanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse, Mahtab Khodadadi, Kiran M. Ali, Suh Hee Cook, Bryson T. Proctor, Tanya Upadhyay, Daxian Zha, Fatema Tuj Jahura, Marziyeh Boosaliki, Jessica M. Gluck   +9 more
wiley   +1 more source

SARS-CoV-2 variant replacement constrains vaccine-specific viral diversification. [PDF]

Virus Evol
Dearlove BL, Fries AC, Epsi NJ, Richard SA, Ganesan A, Huprikar N, Lindholm DA, Mende K, Colombo RE, Colombo C, Bai H, Larson DT, Ewers EC, Lalani T, Smith AG, Berjohn CM, Maves RC, Jones MU, Saunders D, Maldonado CJ, Mody RM, Bazan SE, Tribble DR, Burgess T, Simons MP, Agan BK, Pollett SD, Rolland M.   +27 more
europepmc   +1 more source

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

Advanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal, Remington M. Martinez, Georgia T. Helein, Montserrath G. Ibarra Rivera, Rodolfo Martinez Jr., Jenna L. Sumey, Steven R. Caliari, Christopher B. Highley   +7 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

SARS-CoV-2 infection and sleep health in Military Health System beneficiaries. [PDF]

Sleep Adv
Pollett S, Richard S, Hone E, Jones M, Ganesan A, Lindholm DA, Mende K, Edwards MS, Colombo RE, Larson D, Mody R, Tribble D, Burgess T, Agan B, Lee RU.   +14 more
europepmc   +1 more source

Antiretroviral Therapy Within 2 Years of HIV Acquisition Is Associated With Fewer Viral Blips: A Retrospective Analysis of More Than 20 Years of Data From the US Military HIV Natural History Study. [PDF]

Clin Infect Dis
Crowell TA, Hsieh HC, Wang X, Chu X, Gayle B, Berjohn CM, Blaylock JM, Yabes JM, Larson DT, Powers JH, O'Connell RJ, Ganesan A, Agan BK, Infectious Disease Clinical Research Program HIV Working Group .   +13 more
europepmc   +1 more source

Gastrointestinal manifestations in Williams syndrome: A prospective analysis of an adult and pediatric cohort. [PDF]

Am J Med Genet A
Boechler M, Fu YP, Raja N, Ruiz-Escobar E, Nimmagadda L, Osgood S, Levin MD, Hadigan C, Kozel BA.   +8 more
europepmc   +1 more source

Population genomics of Aedes albopictus across remote Pacific islands for genetic biocontrol considerations. [PDF]

PLoS Negl Trop Dis
Seok S, Vorsino AE, Collier TC, Hapairai LK, Jacobsen CM, Hasty JM, Romero-Weaver AL, Buckner EA, LaPointe DA, Leong MKH, Braack L, Tabuloc CA, Chiu JC, Raban R, Akbari OS, Lee Y.   +15 more
europepmc   +1 more source

Spatial Surveillance of Plasmodium falciparum Kelch 13 Mutations Reveals Emerging Artemisinin Resistance in Kenya

Akala HM, Opot BH, Juma DW, Okoth RO, Mwalo M, Amwoma JG, Salim FA, Maisiba R, Yeda R, Mwakio EW, Chemwor G, Juma JA, Okudo CO, Egbo TE, Njoroge D, Ohaga MM, Cheruiyot AC, Kandie R, Keitany K, Mahugu S, Schneider KA, Osoti V, Wamae K, Obilo MA, Ng’ang'a GK, Garges EC, Andagalu B, Kamau E, Ochola-Oyier LI, Ogutu BR.   +29 more
europepmc   +1 more source