Results 41 to 50 of about 5,197 (334)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A planar-diode frequency tripler at 1.9THz [PDF]

IEEE MTT-S International Microwave Symposium Digest, 2003, 2003
A fix-tuned 1.9 THz frequency tripler utilizing membrane based GaAs Schottky diodes has been designed and fabricated. The chips are three microns thick with no supporting frame. One micron thick beam leads are used to ground the diodes and to hold the circuit in a split-waveguide block.
A. Maestrini, J. Ward, J. Gill, G. Chattopadhyay, F. Maiwald, K. Ellis, H. Javadi, I. Mehdi   +7 more
openaire   +1 more source

Cryogen-Free dissolution Dynamic Nuclear Polarization polarizer operating at 3.35 T, 6.70 T and 10.1 T [PDF]

, 2018
Purpose: A novel dissolution dynamic nuclear polarization (dDNP) polarizer platform is presented. The polarizer meets a number of key requirements for in vitro, pre-clinical and clinical applications.
Ardenkjaer-Larsen, Jan Henrik, Bowen, Sean, Nielsen, Niels Chr., Petersen, Jan Raagaard, Rybalko, Oleksandr, Ullisch, Marcus, Vinding, Mads Sloth   +6 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A Breakdown Voltage Multiplier for High Voltage Swing Drivers [PDF]

, 2007
A novel breakdown voltage (BV) multiplier is introduced that makes it possible to generate high output voltage swings using transistors with low breakdown voltages. The timing analysis of the stage is used to optimize its dynamic response.
Hajimiri, Ali, Mandegaran, Sam
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Microwave Frequency Tripler using InGaAs HEMT Transistor

Procedia Manufacturing, 2020
Abstract In this work, a 3x frequency multiplier in microstrip technology is presented. The frequency multiplier is used to generate 17.4GHz signal by multiplying 5.8GHz input and by using Indium gallium arsenide (InGaAs) High Electron Mobility Transistor (MGF4918D). The input and output reflection coefficients (S11 and S22) are less than -30 dB. The
Moustapha El Bakkali, Naima Amar Touhami, Taj-eddin Elhamadi   +2 more
openaire   +1 more source

Утроение частоты в транзисторних СВЧ генератора [PDF]

, 2010
Розглянутий стан розробки потроювачів частоти. Показано, що створення генераторів-потроювачів частоти знаходиться ще у стадії наукових досліджень. Фірмами випускаються пристрої за схемою: генератор, буфер, підсилювач-потроювачThe frequency tripler state ...
Kotserzhinsky, B. A., Коцержинский, Б. А., Коцержинський, Б. О.   +2 more
core  

Full 3D modelling of pulse propagation enables efficient nonlinear frequency conversion with low energy laser pulses in a single-element tripler [PDF]

, 2017
Although new optical materials continue to open up access to more and more wavelength bands where femtosecond laser pulses can be generated, light frequency conversion techniques are still indispensable in filling the gaps on the ultrafast spectral scale.
Kardas, TM, Nejbauer, M, Radzewicz, C, Resan, B, Wasylczyk, P, Wnuk, P   +5 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source