Results 91 to 100 of about 2,022,125 (263)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Efficient Algorithms for Mining Frequent Patterns from Sparse and Dense Databases

open access: yesJournal of Intelligent Systems, 2015
In this article, we present a new approach for frequent pattern mining (FPM) that runs fast for both sparse and dense databases. Two algorithms, FEM and DFEM, based on our approach are also introduced.
Vu Lan, Alaghband Gita
doaj   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

Mining frequent patterns for AMP-activated protein kinase regulation on skeletal muscle

open access: yesBMC Bioinformatics, 2006
Background AMP-activated protein kinase (AMPK) has emerged as a significant signaling intermediary that regulates metabolisms in response to energy demand and supply.
Chen Yi-Ping, Chen Qingfeng
doaj   +1 more source

A numerical method for frequent pattern mining [PDF]

open access: yes, 2009
Frequent pattern mining is one of the active research themes in data mining. It plays an important role in all data mining tasks such as clustering, classification, prediction, and association analysis.
Mamat, Ali   +3 more
core  

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

A Novel Internet of Things-Centric Framework to Mine Malicious Frequent Patterns

open access: yesIEEE Access, 2019
There are a number of research challenges associated with Internet of Things (IoT) security, and one of these challenges is to design novel frameworks to mine malicious frequent patterns for identifying misuse and detecting anomalies without incurring ...
Nighat Usman   +7 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

THE DISCOVERY OF TOP-K DNA FREQUENT PATTERNS WITH APPROXIMATE METHOD

open access: yesMalaysian Journal of Computing, 2014
Top-k frequent pattern discovery is indeed an association analysis concerning automatic extraction of the k most correlated and interesting patterns from large databases.
Nittaya Kerdprasop, Kittisak Kerdprasop
doaj   +1 more source

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