Results 181 to 190 of about 635,391 (212)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Associations Between Diet, Metabolic Profile, and Cognitive Function in Men with Schizophrenia and Healthy Controls: Evidence from a Comparative Study. [PDF]

Nutrients
Krysta K, Trędzbor B, Martyniak E, Cieślik A, Koźmin-Burzyńska A, Piekarska-Bugiel K, Bieś R, Skałacka K, Drzyzga K, Krzystanek M.   +9 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Injury Patterns in Soccer-Induced Maxillofacial Fractures and Ocular Trauma: A Narrative Review. [PDF]

Sports Med Open
Mergoum AM, Lentner J, Echter B, Roskam J, Hamilton GS, Smith JD.   +5 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Panoramic radiographic prevalence of dental developmental anomalies and jaw lesions in Mallorca, Spain: a retrospective cross-sectional study. [PDF]

Front Oral Health
Vallejos-Rojas D, Shabaka S, Llabrés P, Sparice E, Riutord-Sbert P, Piña M.   +5 more
europepmc   +1 more source

Association Between Intergenerational Relationship With Adult Children and Anxiety-Depression Comorbidity Symptoms in Older Women in China: A National Study Using Latent Profile Analysis. [PDF]

Depress Anxiety
Huang Z, Ren J, Tang H, Qiu G, Yang B, Wang Y, Zhou H.   +6 more
europepmc   +1 more source