Results 181 to 190 of about 34,617 (237)

Probabilistic Risk-Benefit Profile of Ticagrelor Monotherapy After Short Dual Antiplatelet Therapy: A Bayesian Analysis of the ULTIMATE-DAPT Trial. [PDF]

Clin Pharmacol Ther
Yang N, Xie X, Guo N, Li L, Deng N, Wang X, Yang L, Gao H.   +7 more
europepmc   +1 more source

Efficacy and Safety of Oral Non‐Statin Lipid‐Lowering Therapies in Dyslipidaemia: A Systematic Review and Network Meta‐Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
A network meta‐analysis of 43 randomized trials showed that oral combination therapies, particularly obicetrapib plus ezetimibe and bempedoic acid plus ezetimibe, achieved the greatest LDL‐C reduction with reassuring safety profiles, supporting their use as effective oral alternatives for patients with dyslipidaemia. ABSTRACT Introduction Dyslipidaemia
Tamer Hodrob, Reem J. Saad, Aya Hamdy, Mariam Saleh Alheneedy, Ahmed Mohamed Shehata Abdelfattah Elsayed, Elsaghir Ghazy, Hazem Ayesh   +6 more
wiley   +1 more source

Accounting for Biases in the Analysis of Building Damage Data for the 2023 M7.8 Türkiye/Syria Earthquake Sequence

Earthquake Spectra, Volume 42, Issue 4, November 2026.
In the aftermath of a large earthquake, several practical constraints affect the systematic collection of data for assessing building damage. The available data are therefore typically incomplete, frequently missing key information such as the type of construction, age and geographic location.
Max Anderson Loake, Kishor S. Jaiswal
wiley   +1 more source

A Bayesian analysis of finerenone in heart failure with mildly reduced and preserved ejection fraction: a pre-specified analysis of FINEARTS-HF. [PDF]

Eur Heart J Cardiovasc Pharmacother
Henderson AD, Docherty KF, Talebi A, Kondo T, Petrie MC, Claggett BL, Desai AS, Vaduganathan M, Atherton JJ, Bauersachs J, Schou M, Verma S, Lam CSP, Pitt B, Senni M, Shah SJ, Voors AA, Zannad F, Brinker M, Amarante F, Rohwedder K, Lay-Flurrie J, Solomon SD, McMurray JJV, Jhund PS.   +24 more
europepmc   +1 more source

The Addition of Concurrent Immune Checkpoint Inhibitors for Chemoradiotherapy With Consolidative Immune Checkpoint Inhibitors in Unresectable Cancers: A Systematic Review and Meta‐Analysis

International Journal of Cancer, Volume 159, Issue 9, Page 2262-2277, 1 November 2026.
Currently, there are at least 30 ongoing clinical trials in the enrollment phase to evaluate adding concurrent ICIs to the PACIFIC regimen for a variety of solid tumors. Considering the lack of head‐to‐head comparative studies, this meta‐analysis aims to investigate the differences in efficacy between adding and not adding concurrent ICIs to CRT ...
Xu Tong, Zhenting Liu, Xiaoxiang Zhou, Nan Bi, Yibo Gao   +4 more
wiley   +1 more source

Precision therapy for endotoxic septic shock: a step toward personalized treatment from EUPHAS to TIGRIS. [PDF]

Acute Crit Care
Lee SH.
europepmc   +1 more source

Age-Related Differences in Naming Latency Variability. [PDF]

J Cogn
Costantini S, Fuhrmeister P, Bürki A, Lampe LF.   +3 more
europepmc   +1 more source

A Practical Guide to Optimal Adaptive Two‐Stage Designs for Various Endpoint Types

Pharmaceutical Statistics, Volume 25, Issue 6, November/December 2026.
ABSTRACT Adaptive designs are frequently used to adjust sample sizes based on interim data, ensuring reliable conclusions while protecting resources. To maximize trial efficiency, design parameters can be optimized to minimize an objective function (e.g., the expected sample size) while rigorously controlling overall error rates or further operating ...
Nico Bruder, Jan Meis, Maximilian Pilz, Meinhard Kieser   +3 more
wiley   +1 more source

Basket and umbrella trials in pediatric precision medicine: a systematic review of designs, opportunities, and challenges. [PDF]

BMC Med Res Methodol
Khan MR, Stendardo M, Bressan S, Vedovelli L, Berchialla P, Baldi I, Gregori D, Azzolina D.   +7 more
europepmc   +1 more source

Infant social withdrawal with parents and strangers—The role of parental sensitivity and depression

British Journal of Developmental Psychology, Volume 44, Issue 4, Page 861-876, November 2026.
Abstract Infant social withdrawal is an early indicator of infant distress linked to adverse socio‐emotional development. We hypothesized that parental sensitivity moderates an association between parental depression (PPD) and infant social withdrawal.
Maja Rudling, Anne Christine Stuart, Johanne Smith‐Nielsen, Ida Egmose, Katrine Røhder, Mette Skovgaard Væver   +5 more
wiley   +1 more source