Results 51 to 60 of about 34,617 (237)

The effect of antiseizure medications on the exposure to combined oral contraceptives: A systematic review and network meta‐analysis

Epileptic Disorders, EarlyView.
Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen, Amnah Omar Mahajna, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Re‐evaluating impaired consciousness in temporal lobe epilepsy: The role of language dominance and network reorganization

Epilepsia, EarlyView.
Abstract Objective Temporal lobe epilepsy (TLE) frequently affects clinically‐classified ictal consciousness, which the 2025 International League Against Epilepsy (ILAE) classification operationalizes through clinical assessment of awareness and responsiveness.
Radheshyam Stepponat, Marc Berger, Laurin Schäfer, Laura Flamm, Kathrin Kollndorfer, Silvia Bonelli, Gregor Kasprian, Ekaterina Pataraia, Florian Ph. S. Fischmeister   +8 more
wiley   +1 more source

Sample Size Estimation for Non-Inferiority Trials: Frequentist Approach versus Decision Theory Approach.

PLoS ONE, 2015
BackgroundNon-inferiority trials are performed when the main therapeutic effect of the new therapy is expected to be not unacceptably worse than that of the standard therapy, and the new therapy is expected to have advantages over the standard therapy in
A C Bouman, A J ten Cate-Hoek, B L T Ramaekers, M A Joore   +3 more
doaj   +1 more source

The spatial learning task of Lhermitte and Signoret: Marker of bilateral hippocampal dysfunction in temporal lobe epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Bilateral hippocampal compromise in temporal lobe epilepsy (TLE) substantially increases the risk of significant adverse memory outcomes following unilateral anterior temporal lobectomy and may contraindicate surgery. The Spatial Learning Task (SLT) of Lhermitte and Signoret (1972) is a simple object–location arbitrary associative ...
Andy Sitoh, David Weintrob, Jacqueline F. I. Anderson, Marie F. O'Shea, Graeme D. Jackson, Piero Perucca, Chris Tailby   +6 more
wiley   +1 more source

Effect of volume for injection of the 15th to 16th thoracic interspinous space: An ex vivo study

Equine Veterinary Journal, EarlyView.
Abstract Background Impinging (overriding) spinous processes (ISPs) are commonly identified in horses with back pain. Diagnostic analgesia is widely used as the clinical reference standard for confirming association with clinical signs of back pain, but the specificity of dorsal spinous region diagnostic analgesia remains poorly understood.
Virginia Melly, Kara A. Brown, Julie Engiles, Holly L. Stewart, Darko Stefanovski, Kathryn W. Bills, Elizabeth Davidson   +6 more
wiley   +1 more source

PARAMETER ESTIMATION OF LOGNORMAL AND PARETO TYPE I DISTRIBUTIONS USING FREQUENTIST AND BAYESIAN INFERENCES

Barekeng
Extreme events are events that rarely occur but they cause substantial losses. Insurance companies need to take extreme events into account in risk management because extreme events can have a negative impact on the company's financial health.
Jenisha Then, Ferry Jaya Permana, Benny Yong   +2 more
doaj   +1 more source

Comparison of Bayesian and frequentist methods for prevalence estimation under misclassification

BMC Public Health, 2020
Background Various methods exist for statistical inference about a prevalence that consider misclassifications due to an imperfect diagnostic test.
Matthias Flor, Michael Weiß, Thomas Selhorst, Christine Müller-Graf, Matthias Greiner   +4 more
doaj   +1 more source

Nonparametric Regression for Cost‐Effectiveness Analyses With Observational Data—A Tutorial

Health Economics, EarlyView.
ABSTRACT Healthcare decision‐making often requires selecting among multiple treatment options under budget constraints, particularly when one option is more effective but also more costly. Cost‐effectiveness analysis (CEA) provides a framework for evaluating whether the health benefits of a treatment justify its additional costs.
Jonas Esser, Mateus Maia, Judith E. Bosmans, Johanna Maria van Dongen   +3 more
wiley   +1 more source

Bayesian Methodologies with pyhf [PDF]

EPJ Web of Conferences
bayesian_pyhf is a Python package that allows for the parallel Bayesian and frequentist evaluation of multi-channel binned statistical models. The Python library pyhf is used to build such models according to the HistFactory framework and already ...
Feickert Matthew, Heinrich Lukas, Horstmann Malin   +2 more
doaj   +1 more source

Risk factors for not proceeding to reconstructive surgery after female genital mutilation: A cohort study of 220 women in a specialized referral center

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study identifies factors associated with not proceeding to clitoral reconstructive surgery among women with female genital mutilation (FGM) enrolled in a specialized surgical pathway. Methods A retrospective cohort study was conducted at a multidisciplinary referral center in Montreuil, France, between January 2021 and December ...
Félicia Joinau‐Zoulovits, Maëlle Silvestre De Sacy, Bruno Renevier, Sarah Abramowicz   +3 more
wiley   +1 more source