Results 161 to 170 of about 6,603,997 (313)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Demand Elasticities for Fresh Fruit at the Retail Level [PDF]

open access: yes
The obesity epidemic in the US and elsewhere has re-doubled efforts to understand determinants of the quality of consumers' diets. Part of the discussion has centered on the potential of "fat taxes" and/or the subsidization of the purchase of fresh ...
Eales, James S., Durham, Catherine A.
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

A PROBIT MODEL ANALYSIS OF FACTORS AFFECTING CONSUMPTION OF FRESH SWEET CORN IN MAJOR U.S. MARKETS [PDF]

open access: yes
In an effort to more effectively utilize its resources to promote fresh sweet corn, the Fresh Supersweet Corn Council contracted with the Florida Agricultural Market Research Center (FAMRC) of the University of Florida to conduct a comprehensive consumer
Morgan, Kimberly L.   +3 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

PRICE ASYMMETRY IN THE UNITED STATES FRESH TOMATO MARKET [PDF]

open access: yes
This paper analyzes pricing relationships between the producer, wholesale and retail levels of the U.S. fresh tomato industry. The results indicate that price transmission is unidirectional from producer to retail.
Renwick, Alan W.   +2 more
core  

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