Results 51 to 60 of about 9,013 (298)

Intermittency phenomena in electrical connectors [PDF]

open access: yes, 2001
Fretting is known to be a major cause of contact deterioration and failure, particularly in tin-plated contacts. During fretting the contact resistance generally increases slowly with time.
Swingler, Jonathan   +4 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Influence of roughness on contact interface in fretting under dry and boundary lubricated sliding regimes

open access: yes, 2009
This paper presents experimental results of wear process under dry and boundary lubricated metallic (AISI 1034/AISI 52100) contacting bodies with different surfaces morphologies subjected to a wide range of kinematic fretting conditions.
Mathia, T.G.   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Critical Plane Methodology for Intelligent Prediction of Fretting Fatigue Lifetime Based on Shear Strain Dynamics

open access: yesIEEE Access
An approach based on refined critical plane methodology to fretting fatigue lifetime prediction for structures was proposed. A new shear stress-strain interaction (SSI) critical plane equation is developed, predicated on shear strain energy for ...
Wen Zhou   +6 more
doaj   +1 more source

Finite Element Simulation and Fretting Wear Prediction of a Tenon Connection Structure

open access: yesLubricants, 2023
A tenon connection structure is widely used for the blade-disk connection in turbomachinery, and its ability to resist wear influences operation life.
Zexin Zhang   +4 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Degradation of road tested automotive connectors [PDF]

open access: yes, 2000
The automotive environment is particularly demanding on connector performance, and is characterized by large temperature changes, high humidity and corrosive atmospheres.
Swingler, J., McBride, J.W., Maul, C.
core   +1 more source

Effect of Ultrasonic Surface Rolling on the Fretting Wear Property of 7075 Aluminum Alloy

open access: yesMetals, 2023
This paper investigates the effect of ultrasonic surface rolling (USR) on the fretting wear properties of the 7075 aluminum alloy. A white light interferometer, Vickers hardness tester, and X-ray diffractometer were employed to comparatively analyze the ...
Qiwen Xiong   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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