Results 111 to 120 of about 4,355 (175)

Development of a secretable frataxin for enhanced efficacy in treating Friedreich's Ataxia. [PDF]

Mol Ther Adv
DuBreuil DM, Fleming M, Parikh Y, Woo M, Bu J, Ayloo S, Langohr IM, Bangari DS, Mueller C, Ramachandran S.   +9 more
europepmc   +1 more source

Oxidative Stress and Antioxidant Therapies in Friedreich's Ataxia. [PDF]

Cells
Jiménez-Jiménez FJ, Alonso-Navarro H, García-Martín E, Cárcamo-Fonfría A, Martín-Gómez MA, Agúndez JAG.   +5 more
europepmc   +1 more source

Autophagy activation by urolithin-a derivative UA-36 mitigates Friedreich's ataxia pathologies induced by frataxin deficiency. [PDF]

Mol Biomed
Gong Q, Liu T, Han X, Zhang R, Liu X, Xiong B, Ali T, Huang J, Xie Y, Li S, Yang X.   +10 more
europepmc   +1 more source

Friedreich’s Ataxia: Phenotype and Genotype in Eleven Patients

, 2006
Introduction:- Friedreich’s ataxia is anautosomal recessive disease due to a mutationin gene X25. This gene codes for frataxin and itis located on chromosome 9. The disease iscaused by a triplet particular sequence of bases(GAA).
Juan Carlos Prieto, Elizabeth Vargas, Clemencia Durán, Victoria Eugenia Villegas, Olga Lucía Pedraza   +4 more
core  

Validation of circulating miR-323a-3p and miR-625-3p to classify hypertrophic cardiomyopathy in Friedreich's ataxia. [PDF]

Sci Rep
Ibáñez-Cabellos JS, Baviera-Muñoz R, Alemany-Perna B, Sivera R, Bataller L, Cesar S, González-Cabo P, García-Giménez JL, Pallardó FV, Seco-Cervera M.   +9 more
europepmc   +1 more source

Friedreich’s Ataxia: Phenotype and Genotype in Eleven Patients

, 2014
Introducción: La ataxia de Friedreich (FRDA) es una enfermedad autosómica recesiva debida a una mutación en el gen X25. Dicho gen está localizado en el cromosoma 9 y codifica para la proteína frataxina.
Vargas, Elizabeth, Prieto, Juan Carlos, Pedraza, Olga Lucía, Durán, Clemencia, Villegas Gálvez, Victoria Eugenia   +4 more
core  

Microgliopathy as a primary mediator of neuronal death in models of Friedreich's Ataxia. [PDF]

Nat Commun
Pernaci C, Johnson A, Gillette S, Warden AS, McCormick C, Weiser-Novak S, Ramirez G, Broersma EH, Mishra P, Sivakumar A, Cherqui S, Coufal NG.   +11 more
europepmc   +1 more source

The TRKB Agonist 7,8-dihydroxyflavone Alleviates DNA Damage and Apoptosis in a Neuronal Cell Model of Friedreich's Ataxia. [PDF]

Mol Neurobiol
Galán-Cruz J, Vicente-Acosta A, Loría F, Díaz-Nido J, Herranz-Martín S.   +4 more
europepmc   +1 more source

Human pluripotent stem cell models of Friedreich's ataxia: innovations, considerations, and future perspectives. [PDF]

Stem Cell Res Ther
Nguyen HT, Napierala M, Napierala JS.
europepmc   +1 more source

Perspectives on current models of Friedreich's ataxia. [PDF]

Front Cell Dev Biol, 2022
Kelekçi S, Yıldız AB, Sevinç K, Çimen DU, Önder T.   +4 more
europepmc   +1 more source