Results 231 to 240 of about 218,508 (297)

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Innovative Solutions for Obesity: Evaluating gastric bypass stents in Postlaparoscopic Sleeve Gastrectomy Weight Management. [PDF]

Endosc Int Open
Li Z, Nie Y, Wang P, Liu B, Zhou B, Zhang N, Wang S, Chou S, Wang Z, Meng H.   +9 more
europepmc   +1 more source

Dimple‐Encoded Reprogrammable Origami

Advanced Science, EarlyView.
Local snap‐through of bistable dimples turns flat elastic sheets into reprogrammable origami structures. Interaction‐guided dimple arrays act as angle‐programmable hinge bands, enabling one sheet to morph into distinct polygonal and three‐dimensional configurations while retaining stable shapes for deployable and protective functions.
Qun Zhang, Weicheng Huang, Amir Hajiyavand, Hyunyoung Kim, Claire Dancer, Karl Dearn, Mingchao Liu   +6 more
wiley   +1 more source

Garden of Emotions: a humanities-informed approach to mitigating the social determinants of health in at-risk children and youth. [PDF]

Paediatr Child Health
LeBlanc D, Nagel JM, Fana N, Lunney S, Gander S.   +4 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Correction: Impact of short-term exposure to high ambient temperature on pulmonary tuberculosis: a 5-year time-series analysis in Beijing. [PDF]

Front Public Health
Li S, Guo F, Wang C, Liu R, Qi W.
europepmc   +1 more source

Substitution or Multiplication? How Personal Networks Modify the Association Between Perceived Neighbourhood Social Capital and Loneliness: A Cross-Sectional Analysis of 124,175 adults in England

Haoran L, Altalib S, Fadoju A, Jerjes W, Tristan A, El-Osta A.   +5 more
europepmc   +1 more source

The exploitation argument against artificial companionship. [PDF]

AI Ethics
VandenHombergh J.
europepmc   +1 more source

Mental health outcomes of a peer support programme for prosthesis and orthosis users in Cambodia: An explanatory sequential mixed-methods study. [PDF]

Glob Ment Health (Camb)
Best P, Maddock A, Heang T, Ean N, Kheng S, Ramstrand N.   +5 more
europepmc   +1 more source