Results 111 to 120 of about 149,921 (252)

Computational Characterization of the Role of LEM2/LaminA Interactions on the Stability of BAF‐Dimer Using Molecular Simulations

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The effect of the presence of the BAF‐binding LEM‐domain and LaminA Ig‐fold on the stability of the BAF dimer was studied qualitatively using non‐equilibrium pull simulations and quantitatively through the calculation of the potential of mean force profile along BAF–BAF separation distance.
Aswin Vinod Muthachikavil   +2 more
wiley   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler   +7 more
wiley   +1 more source

Development of 4D printing and its performance testing methods

open access: yesResponsive Materials, EarlyView.
This paper reviews the molding methods of 4D printing and its applications in various fields, with emphasis on 4D printing performance testing methods. Abstract 4D printing is a cutting‐edge additive manufacturing technology that introduces the time dimension, allowing printed objects to have dynamic, changeable properties, functions or shapes ...
Guiwei Li   +8 more
wiley   +1 more source

Identity Play: Middle School Youths' Provisional Self‐Making in Horizon‐Expanding STEM Spaces

open access: yesScience Education, EarlyView.
ABSTRACT This study introduces identity play as an analytic construct for science education to explore improvisational dimensions of middle school students' STEM identity development in multiple out‐of‐school learning experiences focused on environmental problem‐solving.
Heidi B. Carlone, Alison K. Mercier
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

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