Results 61 to 70 of about 183,256 (304)
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Journal of Pharmaceutical Policy and Practice, 2020 In the fight against COVID-19, frontline health workers have been vital to keeping the pandemic at bay, but recognition of individual professions’ efforts have been inconsistent at all levels. Pharmacists around the world have continued to provide direct
Ali Elbeddini +3 more
doaj +1 more source
Managing engagement behaviors in a network of customers and stakeholders: evidence from the nursing home sector [PDF]
, 2013 Firms striving for long-term profitability need to build stronger customer-firm relationships by getting their customers more engaged with the firm. One path to this end is introducing practices to manage different forms of customer engagement behaviors (
Gemmel, Paul +2 more
core +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Lessons learned from the coronavirus health crisis in the nordic countries
European Psychiatry, 2021 Body The COVID-19 pandemic has had an unprecedented influence on the global economy and population health. Vigorous, well-designed studies with complete, long-term follow-up of high risk groups including COVID-19 patients, their families and frontline ...
U. Valdimarsdóttir
doaj +1 more source
Counting the Invisible Man: Black Males and the 2010 Census [PDF]
, 2011 iCount was a campaign to increase the expected low participation rates of black males in the 2010 census. This briefing paper provides an overview of that effort and lessons learned that could guide strategy for increased participation in the 2020 ...
Karen Cherfils, Ryan Bowers
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Blood AdvancesAbstract Follicular lymphoma (FL) and marginal zone lymphoma (MZL) often have long overall survival (OS), however, high-grade transformation (HGT) to diffuse large B-cell lymphoma markedly reduces survival. The roles of upfront treatment vs observation on the incidence and outcome of HGT remain unclear.
Jorge A. Florindez +4 more
openaire +2 more sources
Advanced Materials, EarlyView.An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang +5 more
wiley +1 more source
Frontline Health Workers: The Best Way to Save Lives, Accelerate Progress on Global Health, and Help Advance U.S. Interests [PDF]
, 2012 Argues for training, equipping, and supporting community-based health workers, midwives, pharmacists, nurses, and doctors who provide care for rural populations in the developing world as a cost-efficient way to advance global health and ...
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