Results 201 to 210 of about 98,352 (316)

Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature

Brain and Behavior, Volume 16, Issue 2, February 2026.
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore, Martina Marcaccio, Ilaria Di Pompeo, Massimo Marano, Giuseppe Curcio   +4 more
wiley   +1 more source

Additional file 3 of GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

Ignacio Silva-Llanes, Lilia A. Smith, Aaron Abdelkader-Guillén, José Jiménez-Villegas, David Sarrió, Moreno‐Bueno Gema, Isabel Lastres-Becker   +6 more
openalex   +1 more source

The Genetics of Monogenic Frontotemporal Dementia [PDF]

, 2015
Leonel Tadao Takada
openalex   +1 more source

Social Cognition in Community Dwelling Persons With Dementia; Is Facial Emotion Recognition Related to Proxy Rated Empathy and Aggression?

International Journal of Geriatric Psychiatry, Volume 41, Issue 2, February 2026.
ABSTRACT Objectives Aggressive behaviour and decreased empathy occur in many dementia syndromes. This may be related to lowered overall cognitive functioning which is a common feature of dementia. However, to date, the role of social cognitive impairments such as facial emotion recognition (FER) deficits in dementias other than behavioural variant ...
Aafra T. Ter Horst, Marleen J. J. Gerritsen, Jacoba M. Spikman   +2 more
wiley   +1 more source

Inheritance of Frontotemporal Dementia

, 1999
Tiffany W. Chow, Bruce L. Miller, Vivian N. Hayashi, Daniel H. Geschwind   +3 more
openalex   +2 more sources

segcsvdPVS: A Convolutional Neural Network‐Based Tool for Quantification of Enlarged Perivascular Spaces (PVS) on T1‐Weighted Images

Human Brain Mapping, Volume 47, Issue 2, February 1, 2026.
segcsvdPVS is a novel convolutional neural network (CNN)‐based perivascular spaces (PVS) segmentation tool for T1‐weighted images based on a hierarchical segmentation framework developed with strategically designed inputs and robust training. It demonstrates high accuracy, consistent performance, and improved detection of age‐related changes in PVS ...
Erin Gibson, Joel Ramirez, Lauren Abby Woods, Stephanie Berberian, Julie Ottoy, Christopher J. M. Scott, Vanessa Yhap, Fuqiang Gao, Roberto Duarte Coello, Maria Valdes Hernandez, Anthony E. Lang, Carmela M. Tartaglia, Sanjeev Kumar, Malcolm A. Binns, Robert Bartha, Sean Symons, Richard H. Swartz, Mario Masellis, Navneet Singh, Bradley J. MacIntosh, Joanna M. Wardlaw, Sandra E. Black, ONDRI Investigators, ADNI, CAHHM Investigators, CAIN Investigators, colleagues from the Foundation Leducq Transatlantic Network of Excellence, Andrew S. P. Lim, Maged Goubran   +28 more
wiley   +1 more source

Identifying Susceptibility Genes and Shared Genetic Architecture for Longevity and Muscle Weakness

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Longevity and muscle strength are heritable traits, and age‐related muscle weakness is a major contributor to disability in older adults. However, the susceptibility genes and shared genetic mechanisms underlying lifespan and sarcopenia remain unclear.
Yilong Lin, Yun Zhang, Shengjie Lin, Songsong Wang, Zhiqiang Que, Yue Zhang, Jing She, Ruidan Zhao, Jiawei Chen, Anqi Qiu, Shinan Wu, Ruiqin Yang, Liyi Zhang, Qingmo Yang   +13 more
wiley   +1 more source

Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]

, 2018
Benitez, Bruno A, Budde, John, Cooper, Breanna, Cruchaga, Carlos, David, Albert A, Diez-Fairen, Monica, Dube, Umber, Fernandez, Maria V, Ibanez, Laura, Ortega-Cubero, Sara, Pastor, Pau, Perlmutter, Joel S   +11 more
core   +2 more sources

Survival in the pre-senile dementia frontotemporal lobar degeneration with TDP-43 proteinopathy: effects of genetic, demographic and neuropathological variables [PDF]

, 2016
Richard A. Armstrong
openalex   +1 more source

Multi‐Omics Analysis of Human Blood Cells Reveals Unique Features of Age‐Associated Type 2 CD8 Memory T Cells

Aging Cell, Volume 25, Issue 2, February 2026.
Aging drives the accumulation of CXCR3‐ central memory CD8 T cells that exhibit Th2‐like transcriptional and epigenetic programs. These cells display a pathogenic Th2‐skewed profile and are associated with age‐related diseases, including asthma, chronic liver disease, and type 2 diabetes.
Hiroyuki Matsui, Marlene Cervantes, Mir M. Khalid, Alan Tomusiak, Varun Dwaraka, Jorge Landgrave‐Gomez, Prasanna Vadhana Ashok Kumaar, Qingwen Chen, Jessica Lasky‐Su, Jake Stone, Ritesh Tiwari, Ryan Kwok, Shuntaro Ichikawa, Benjamin D. Ambrose, Rebeccah R. Riley, Genesis Vega Hormazabal, Ariel Adkisson‐Floro, Andreea Cristina Alexandru, Ryan Smith, Birgit Schilling, Herbert G. Kasler, Eric Verdin   +21 more
wiley   +1 more source