Results 131 to 140 of about 30,886 (249)

Comparison of Magnetic Resonance Spectra Acquired With Hybrid PET/MR and Standalone MR Scanners

Journal of Magnetic Resonance Imaging, Volume 62, Issue 6, Page 1854-1865, December 2025.
ABSTRACT Background The effect of the positron emission tomography (PET) modality in hybrid PET/MR scanners on MR spectral quality is unclear. Purpose To evaluate spectral quality, quantification, and repeatability of brain MR spectroscopy (MRS) acquired on PET/MR and standalone MR scanners. Study Type Prospective.
Carter B. Macdonald, Aditya Bhattacharya, Benjamin B. Risk, Taylor M. Zuleger, Sagar Mandava, Ralph Noeske, Candace C. Fleischer   +6 more
wiley   +1 more source

Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics [PDF]

, 2016
Introduction: Reliable cerebrospinal fluid (CSF) biomarkers enabling identification of frontotemporal dementia (FTD) and its pathologic subtypes are lacking.
Beccari, T. (Tommaso), Dopper, E.G.P. (Elise), Durieux-Lu, S. (Sisi), Elias, N. (Naura), Jimenez, C.R. (Connie), Koel-Simmelink, M.J.A. (Marleen), Malekzadeh, A. (Arjan), Meeter, L.H.H. (Lieke), Pham, T.V. (Thang V.), Piersma, S.R. (Sander R.), Pijnenburg, Y.A.L. (Yolande), Swieten, J.C. (John) van, Teunissen, C.E. (Charlotte)   +12 more
core   +1 more source

Plasma Small Extracellular Vesicles with Complement Alterations in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration [PDF]

, 2022
Sonia Bellini, Claudia Saraceno, Luisa Benussi, Rosanna Squitti, Sara Cimini, Martina Ricci, Laura Canafoglia, Cinzia Coppola, Gianfranco Puoti, Clarissa Ferrari, Antonio Longobardi, Roland Nicsanu, Marta Lombardi, Giulia D’Arrigo, Claudia Verderio, Giuliano Binetti, Giacomina Rossi, Roberta Ghidoni   +17 more
openalex   +1 more source

MRI‐DTI Biomarkers Along the Continuum of Behavioral Variant Frontotemporal Dementia

European Journal of Neurology, Volume 32, Issue 12, December 2025.
ABSTRACT Background We investigated whether diffusion tensor imaging (DTI) and atlas‐based volumetry (ABV) could track specific patterns of brain white matter (WM) microstructure and gray matter (GM) volumes in behavioral variant frontotemporal dementia (bvFTD) and amyotrophic lateral sclerosis with frontotemporal dementia (ALS‐FTD).
Marco Michelutti, Hans‐Jürgen Huppertz, Sarah Anderl‐Straub, Heiko Volkmann, Daniele Urso, Benedetta Tafuri, Salvatore Nigro, Paolo Manganotti, Angela Rosenbohm, Albert C. Ludolph, Markus Otto, Giancarlo Logroscino, Hans‐Peter Müller, Jan Kassubek   +13 more
wiley   +1 more source

Behavioral variant frontotemporal dementia in patients with previous severe mental illness: a systematic and critical review

Arquivos de Neuro-Psiquiatria
Objectives: To explore the relationship between severe/serious mental illness (SMI) and the behavioral variant of frontotemporal dementia (bvFTD), as the patterns of symptoms and cognitive performance that characterize both disorders share similarities.
Leandro Boson Gambogi, Henrique Cerqueira Guimarães, Leonardo Cruz De Souza, Paulo Caramelli   +3 more
doaj   +1 more source

Atypical Frontotemporal Dementia Associated With SQSTM1 Gene Mutation: A Clinicopathological Case

Neuropathology, Volume 45, Issue 6, December 2025.
ABSTRACT A 78‐year‐old man presented with a six‐year history of progressive memory decline, initially manifesting as recent memory impairment and mild anomia, which gradually evolved into motor clumsiness, gait disturbances, language difficulties, behavioral changes, and late‐onset parkinsonism. He had been diagnosed with Paget disease of bone (PDB) at
Christian Espinoza‐Vinces, María Victoria Zelaya Huerta, Valle Coca Pueyo, Genoveva Montoya‐Murillo, Ana Patiño‐García, Rafael Villino‐Rodríguez, Ainhoa Atorrasagasti‐Villar, Javier Arbizu, Mario Riverol   +8 more
wiley   +1 more source

Phenotypic heterogeneity of monogenic frontotemporal dementia

Frontiers in Aging Neuroscience, 2015
Frontotemporal dementia (FTD) is a genetically and pathologically heterogeneous disorder characterized by personality changes, language impairment and deficits of executive functions associated with frontal and temporal lobe degeneration.
Alberto eBenussi, Alessandro ePadovani, Barbara eBorroni   +2 more
doaj   +1 more source

Plasma phosphorylated tau 217 and phosphorylated tau 181 as biomarkers in Alzheimer's disease and frontotemporal lobar degeneration: a retrospective diagnostic performance study

Lancet Neurology, 2021
Elisabeth H Thijssen, R. Joie, Amelia Strom, Corrina Fonseca, Leonardo Iaccarino, Amy Wolf, S. Spina, I. Allen, Y. Cobigo, H. Heuer, L. Vandevrede, Nicholas K. Proctor, A. L. Lago, S. Baker, Rajeev Sivasankaran, A. Kieloch, A. Kinhikar, Lili Yu, M. Valentin, A. Jeromin, H. Zetterberg, O. Hansson, N. Mattsson‐Carlgren, Danielle L. Graham, K. Blennow, J. Kramer, L. Grinberg, W. Seeley, H. Rosen, B. Boeve, B. Miller, C. Teunissen, G. Rabinovici, J. Rojas, J. Dage, A. Boxer   +35 more
semanticscholar   +1 more source

A Case of Frontotemporal Lobar Degeneration with Progressive Dysarthria

Behavioural Neurology, 2006
We investigated the evolution of the neurological and neuropsychological characteristics in a right-handed woman who was 53-years-old at the onset and who showed personality changes and behavioral disorders accompanied by progressive dysarthria.
Nami Ihori, Shigeo Araki, Kenji Ishihara, Mitsuru Kawamura   +3 more
doaj   +1 more source

Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia

Neurobiology of Disease
Loss-of-function mutations affecting the lysosomal protein progranulin are a leading cause of frontotemporal dementia. Progranulin mutations cause abnormalities in lysosomal lipid processing, particularly of sphingolipids, major components of neural cell
Nicholas R. Boyle, Stephanie N. Fox, Aniketh S. Tadepalli, Nicholas T. Seyfried, Thomas Kukar, Eliana M. Ramos, Alissa L. Nana, Salvatore Spina, Lea T. Grinberg, Bruce L. Miller, William W. Seeley, Andrew E. Arrant, Erik D. Roberson   +12 more
doaj   +1 more source