Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders
The overlap of symptoms between neurodegenerative and psychiatric diseases has been reported. Neuropsychiatric alterations are commonly observed in dementia, especially in the behavioral variant of frontotemporal dementia (bvFTD), which is the most ...
Roberta eZanardini +3 more
doaj +1 more source
Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency. [PDF]
Objective: To investigate associations between peripheral innate immune activation and frontotemporal lobar degeneration (FTLD) in progranulin gene (GRN) haploinsufficiency. Methods: In this cross-sectional study, ELISA was used to measure six markers of
Allen, Isabel Elaine +16 more
core +2 more sources
Over the past decade, the transactive response DNA-binding protein of 43 kDa (TDP-43) has been recognized as a major protein in normal and pathological ageing, increasing the risk of cognitive impairment and dementia.
Alexandre Bejanin +17 more
semanticscholar +1 more source
PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers [PDF]
Carolina Alquézar +6 more
openalex +1 more source
Plasma Small Extracellular Vesicle Cathepsin D Dysregulation in GRN/C9orf72 and Sporadic Frontotemporal Lobar Degeneration [PDF]
Sonia Bellini +13 more
openalex +1 more source
M. Neumann, Eddie B. Lee, I. Mackenzie
semanticscholar +1 more source
A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes
Importance Cerebrospinal fluid (CSF) core Alzheimer disease (AD) biomarkers have shown an excellent capacity for the in vivo detection of AD. Previous studies have shown that CSF levels of phosphorylated tau (p-tau) also correlate with tau pathology in ...
A. Lleó +9 more
semanticscholar +1 more source
Research progress of behavioral variant frontotemporal dementia
There is no epidemiological data of frontotemporal dementia (FTD) in China. The application of updated diagnostic criteria, publishing of frontotemporal lobar degeneration (FTLD) consensus in China, development of multimodal imaging and biomarkers ...
Xiao-hua GU, Jun XU
doaj
Functional communication ability in frontotemporal lobar degeneration and Alzheimer's disease [PDF]
Isabel Carvalho +2 more
openalex +1 more source
Analyses of Quality of Life in Frontotemporal Lobar Degeneration: Findings from the ALLFTD Consortium [PDF]
Kevin M. Nelson +9 more
openalex +1 more source

