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Fluid Biomarkers of Frontotemporal Lobar Degeneration
2021A timely diagnosis of frontotemporal degeneration (FTD) is frequently challenging due to the heterogeneous symptomatology and poor phenotype-pathological correlation. Fluid biomarkers that reflect FTD pathophysiology could be instrumental in both clinical practice and pharmaceutical trials.
van der Ende, Emma, van Swieten, J.C.
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Epidemiology of Frontotemporal Lobar Degeneration
Dementia and Geriatric Cognitive Disorders, 2004A few epidemiologic studies have dealt with the prevalence of frontotemporal lobar degeneration (FTLD), including Pick’s disease. The aim of this study was to review the epidemiologic studies of FTLD in western countries and to compare them with those in Japan.
Manabu, Ikeda +2 more
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Initial Complaints in Frontotemporal Lobar Degeneration
Dementia and Geriatric Cognitive Disorders, 2004<i>Aims:</i> Frontotemporal lobar degeneration (FTLD) is probably underrecognized. The goal of this study was to investigate initial complaints of both patients and their caregivers at first specialist referral. Also, we tried to assess whether misrecognition of symptoms contributed to diagnostic delay.
Pijnenburg, Yolande A.L. +3 more
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Molecular Pathways of Frontotemporal Lobar Degeneration
Annual Review of Neuroscience, 2010Frontotemporal lobar degeneration (FTLD) is a neurodegenerative condition that predominantly affects behavior, social awareness, and language. It is characterized by extensive heterogeneity at the clinical, pathological, and genetic levels. Recognition of these levels of heterogeneity is important for proper disease management.
Sleegers, Kristel +2 more
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EEG abnormalities in frontotemporal lobar degeneration
Neurology, 2004The EEG appearances in patients with frontotemporal lobar degeneration (FTLD) were compared with those in patients with Alzheimer disease (AD). EEG abnormalities were found in 61% of FTLD patients, with the degree of EEG abnormality increasing with dementia severity.
D, Chan +5 more
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The genetics of frontotemporal lobar degeneration
Current Opinion in Neurology, 2007This review addresses the latest developments in the genetics of frontotemporal lobar degeneration. 'Frontotemporal lobar degeneration' is the clinical term used to describe a heterogeneous neurodegenerative syndrome that includes frontotemporal dementia, semantic dementia, progressive nonfluent aphasia and progressive apraxia.
Pickering-Brown, Stuart +3 more
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Progranulin and frontotemporal lobar degeneration
Acta Neuropathologica, 2007Frontotemporal lobar degeneration is the term used to describe the non-Alzheimer clinical syndromes of frontotemporal dementia, semantic dementia and progressive non-fluent aphasia, regardless of the underlying neuropathological features. Considerable progress has been made in recent years in our understanding of the aetiology of this disorder, notably
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[Frontotemporal lobar degeneration].
Fortschritte der Neurologie-Psychiatrie, 2009J, Diehl-Schmid +8 more
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