Results 111 to 120 of about 272,656 (304)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Temporal and Spatial Variability of Ground Frost Indices in Northeast China
AtmosphereFrost is one of the most frequent, intense, and influential agrometeorological disasters that occurs frequently in Northeast China. The study of the spatiotemporal changes of ground frost is of great significance for farmers and policymakers in Northeast
Ting Wang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Frostwing Co-Operation in Aircraft Icing Research [PDF]
e aerodynamic effects of Cold Soaked Fuel Frost have become increasingly significant as airworthiness authorities have been asked to allow it during aircraft take-off.
Bond, Thomas +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Characteristics of air-cooled heat exchanger with frost formation.
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series B, 1989 In order to clarify the effects of frost formation on the performance of an air-cooled heat exchanger, analyses by a uniform frost formation model and experiments were performed. Using this model, frost thickness and frost density can be estimated from the increase of the pressure drop of the heat exchangers.
Kazuhiko OGAWA, Yu SESHIMO
openaire +2 more sources
Hybrid RANS/LES of plane jets impinging on a flat plate at small nozzle-plate distances [PDF]
, 2012 A k-omega BASED HYBRID RANS/LES (Reynolds-averaged Navier-Stokes/large eddy simulation) model is tested for simulation of plane impinging jets at various nozzle-plate distances (H/B), where H is the distance and B is the slot's width) and various ...
Degroote, Joris +4 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Zhileng xuebao, 2006 The effects of the outdoor air temperature and humidity on the frosting characteristics of the fin - tube evaporator coils of an air source heat pump were investigated experimentally.
郭宪民 +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source