Results 81 to 90 of about 272,656 (304)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Influence of topography and moisture and nutrient availability on green alder function on the low arctic tundra, NT [PDF]
, 2017 The Arctic has warmed by at least 3°C over the past 50 years and this rapid warming is expected to continue. Climate warming is driving the proliferation of shrubs across the tundra biome with implications for energy balance, climate, hydrology, nutrient
Baltzer, Jennifer Lynn, Dr. +1 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Thermal infrared spectroscopy of Europa and Callisto [PDF]
, 2000 The trailing hemispheres of Europa and Callisto were observed at 9–13 μm, and a spectrum of Europa with better spectral resolution and a better signal-to-noise ratio than was previously possible has been derived.
Brown, Michael E., Mills, Franklin P.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The Impact of Personal Attitudes on Cereal Variety Adoption Decisions in Alberta [PDF]
The goal of this study was to help guide development efforts of a current breeding program underway in Saskatoon, Saskatchewan, aimed at producing new cold tolerant cereal varieties.
Cole, Jesse
core +1 more source
Frost and Forest Stand Effects on the Population Dynamics of Asplenium scolopendrium [PDF]
, 2010 Our objective was to analyze which factors are critical for the dynamics of terrestrial Asplenium scolopendrium populations at the northern edge of its distribution.
Bremer, P., Jongejans, E.
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Review on Interfacial Frosting and Anti-/Defrosting Techniques
Zhileng xuebaoInterfacial frosting is ubiquitous in daily life and has many industrial applications. Owing to the poor heat transfer performance induced by packed air pockets, the frost layer usually manifests itself as a thick porous medium, which compromises the ...
Cai Haoting, Zhang Ruimin, Zhao Yugang
doaj
Shuiwen dizhi gongcheng dizhiFrost heave in positive permafrost is a critical factor leading to frost damage of engineering in the cold region. The frost heave process results from the dynamic interaction of hydro-thermal forces.
Hui GE, Chunxiang GUO, Lei ZHANG
doaj +1 more source