Exposing dairy bulls to high temperature-humidity index during spermatogenesis compromises subsequent embryo development in vitro [PDF]
Broekhuijse, Marleen L.W.J. +10 more
core +2 more sources
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Embryonic Stem Cell Research as an Ethical Issue: On the Emptiness of Symbolic Value [PDF]
The debate over human embryonic stem cell research-scientific and clinical prospects as well as ethical implications-became front-page news only after two teams of university researchers reported in November 1998 that they had isolated and cultured human
Quinn, Kevin P.
core +2 more sources
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo +18 more
wiley +1 more source
A comparison of luteal phase support in graduated estradiol/progesterone replacement cycles using intramuscular progesterone alone vs. combination with vaginal suppositories on outcome following frozen embryo transfer [PDF]
V GRAZIANO
openalex +1 more source
P-784 Less obstetric and neonatal outcomes after natural versus artificial cycle frozen embryo transfer [PDF]
F Mol +5 more
openalex +1 more source
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
Efficacy of Intrauterine Infusion of Iodine Glycerol Combined with Antibiotic Therapy on Frozen Embryo Transfer (F-ET) Outcomes in Patients with Chronic Endometritis: A Propensity Score Matching (PSM) Analysis [PDF]
昕雨 杜
openalex +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Pregnancy outcomes following in vitro fertilization using fresh or frozen embryo transfer
Mahvash Zargar +3 more
openalex +1 more source

