Results 51 to 60 of about 53,230 (232)

Cervico-vaginal immunoglobulin G levels increase post-ovulation independently of neutrophils. [PDF]

PLoS ONE, 2014
The prevalence of sexually transmitted infections (STIs) is often higher in females than in males. Although the reproductive cycle profoundly modulates local immunity in the female reproductive tract (FRT) system, significant gaps in our knowledge of the
Katrein Schaefer, Najmeeyah Brown, Paul M Kaye, Charles J Lacey   +3 more
doaj   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Sex hormones regulate tenofovir-diphosphate in female reproductive tract cells in culture.

PLoS ONE, 2014
The conflicting results of recent pre-exposure prophylaxis (PrEP) trials utilizing tenofovir (TFV) to prevent HIV infection in women led us to evaluate the accumulation of intracellular TFV-diphosphate (TFV-DP) in cells from the female reproductive tract
Zheng Shen, John V Fahey, Jack E Bodwell, Marta Rodriguez-Garcia, Angela D M Kashuba, Charles R Wira   +5 more
doaj   +1 more source

Generation of human female reproductive tract epithelium from human embryonic stem cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Recent studies have identified stem/progenitor cells in human and mouse uterine epithelium, which are postulated to be responsible for tissue regeneration and proliferative disorders of human endometrium. These progenitor cells are thought to
Louie Ye, Robyn Mayberry, Camden Y Lo, Kara L Britt, Edouard G Stanley, Andrew G Elefanty, Caroline E Gargett   +6 more
doaj   +1 more source

The human health effects of Florida Red Tide (FRT) blooms : an expanded analysis [PDF]

, 2014
Author Posting. © The Author(s), 2014. This is the author's version of the work. It is posted here by permission of Elsevier for personal use, not for redistribution. The definitive version was published in Environment International 68 (2014): 144-153,
Kirkpatrick, Gary, Hoagland, Porter, Jin, Di, Fleming, Lora E., Beet, Andrew R., Beet, Andrew, Fleming, Lora E, Ullmann, Steven G., Ullmann, Steve, Reich, Andrew, Kirkpatrick, Barbara   +10 more
core   +1 more source

Time-Varying Linkages Between Survey-Based Financial Risk Tolerance and Stock Market Dynamics: Signal Decomposition and Regime-Switching Evidence

Mathematics
This study examines how aggregate financial risk tolerance (FRT), measured from repeated survey responses, co-evolves with stock-market dynamics over time.
Wookjae Heo
doaj   +1 more source

Relationship between Anthropometrics Characteristics and Dynamic Balance in Children of Anand City, Gujarat [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Paediatric physical therapists use a variety of functional balance screening tools developed for adults including the Functional Reach Test (FRT), the Time Up and Go test (TUG), and the Berg Balance Scale (BBS).
Nirav P Vaghela, Jigar N Mehta, Dhruveshi Rana   +2 more
doaj   +1 more source

The effect of Tai Chi on FRT.

, 2014
Subgroup analysis was performed according to whether or not medications were included in the intervention. A random model was used to address the high heterogeneity. FRT, functional reach test.
Xiaogeng Shi (578076), Fuchang Lu (578075), Xinfeng Guo (578077), Xiaojia Ni (578073), Shaonan Liu (578074)   +4 more
core   +1 more source

Isolation and Characterization of Random Citrate Synthase Variants That Increase Acetate Generation by Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A method to select Escherichia coli citrate synthase variants having reduced activity was developed based initially on the increased generation of acid, observed visually by prolonged color change in the pH indicator bromocresol purple. Five hundred fifty‐two potential variants were isolated and each were cultured on glucose as sole carbon ...
Jeffrey K. Dodelin, Ronnie L. Fulton, Abigail E. Rose, Mark A. Eiteman   +3 more
wiley   +1 more source