Results 31 to 40 of about 49,918 (245)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Metsätieteen aikakauskirjaKatsauksessa tarkasteltiin FSC- ja PEFC-metsäsertifiointistandardien vaatimuksia Suomen talousmetsien monimuotoisuuden turvaamiseksi. Vertailimme standardeja keskenään sekä suhteessa aiempiin standardeihin, lainsäädäntöön ja ekologiseen tutkimustietoon ...
Pekka Punttila +3 more
doaj +1 more source
European Journal of Histochemistry, 2010 Folliculostellate cells (FSC) have been reported in pituitary of several mammalian species. FSC morphology and secreted sub- stances have been instrumental to the under- standing of their function.
M. Acosta, V. Filippa, F. Mohamed
doaj +1 more source
Advances in Climate Change Research, 2020 Grassland-based animal husbandry and livestock production is the main contributor to livelihood creation for herdsmen. By using the structural dynamics method, this study quantified the changes in the food supply capacity (FSC) of alpine grassland ...
Yi-Ping FANG
doaj +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Productivity and blast resistance of the androgenic doubled rice haploids Oryza sativa L.
Зерновое хозяйство России, 2023 Most Far Eastern rice varieties are heavily affected by blast, so breeding of resistant samples is of great necessity. The purpose of the current study was to estimate and select androgenic doubled rice haploids Oryza sativa L. with an immune to the rice
M. V. Ilyushko +4 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
An Exploratory Assessment of FSC Chain of Custody Certification Benefits in Croatian Wood Industry
Drvna Industrija, 2016 Croatian State Forest Enterprise covers more than seventy five percent of forest area in the Republic of Croatia and it is the biggest supplier of Croatian wood industry companies.
Kristina Klarić +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source