Results 141 to 150 of about 62,729 (246)

Histone Lactylation Couples FSH-Driven Lactate Metabolism to Mitochondrial Biogenesis by Enhancing HDAC4-Mediated Deacetylation of PGC-1α in Granulosa Cells. [PDF]

open access: yesResearch (Wash D C)
Wu G   +13 more
europepmc   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Magnetic resonance imaging-based adenohypophyseal volume for diagnosing hypothalamic-pituitary-gonadal axis activation in pre- and at-puberty children. [PDF]

open access: yesQuant Imaging Med Surg
Gao S   +11 more
europepmc   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao   +8 more
wiley   +1 more source

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 860-868, March 2026.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee   +5 more
wiley   +1 more source

First Case of Neuroblastoma‐Like Somatic‐Type Malignancy Arising in the Teratomatous Component of a Mixed Non‐Seminomatous Testicular Germ Cell Tumor in an Adult

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Somatic malignant transformation (SMT) in germ cell tumors (GCTs) is a rare but clinically significant event. Among non‐seminomatous germ cell tumors (NSGCTs), teratomas can undergo malignant transformation, with neuroblastoma‐like differentiation being exceptionally rare.
Karl Ziade   +4 more
wiley   +1 more source

Does Walnut Supplementation Have Favourable Effect Apolipoprotein A, B and Blood Pressure? A Systematic Review, Meta‐Analysis and Meta‐Evidence of Randomised Clinical Trials

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
This meta‐analysis of 25 randomised controlled trials demonstrates that walnut consumption significantly lowers apolipoprotein B levels while showing no significant effects on apolipoprotein A1, systolic blood pressure, or diastolic blood pressure. ABSTRACT Backgrounds Many randomised controlled trials (RCTs) have revealed the benefits of walnut on ...
Vali Musazadeh   +4 more
wiley   +1 more source

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