Results 141 to 150 of about 62,729 (246)
Histone Lactylation Couples FSH-Driven Lactate Metabolism to Mitochondrial Biogenesis by Enhancing HDAC4-Mediated Deacetylation of PGC-1α in Granulosa Cells. [PDF]
Wu G +13 more
europepmc +1 more source
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
Magnetic resonance imaging-based adenohypophyseal volume for diagnosing hypothalamic-pituitary-gonadal axis activation in pre- and at-puberty children. [PDF]
Gao S +11 more
europepmc +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee +5 more
wiley +1 more source
Follicle stimulating hormone stimulates farnesyl-diphosphate farnesyltransferase 1 expression through LSD1Ser54p in chicken ovarian granulosa cells. [PDF]
Zhang Y, Zhang M, Liu Q, Jiang Y.
europepmc +1 more source
ABSTRACT Somatic malignant transformation (SMT) in germ cell tumors (GCTs) is a rare but clinically significant event. Among non‐seminomatous germ cell tumors (NSGCTs), teratomas can undergo malignant transformation, with neuroblastoma‐like differentiation being exceptionally rare.
Karl Ziade +4 more
wiley +1 more source
A preliminary investigation of gene expression and levels of FSH, IL-10, and TNF-α and histological staining in natural aging mice. [PDF]
Intan YSN +3 more
europepmc +1 more source
This meta‐analysis of 25 randomised controlled trials demonstrates that walnut consumption significantly lowers apolipoprotein B levels while showing no significant effects on apolipoprotein A1, systolic blood pressure, or diastolic blood pressure. ABSTRACT Backgrounds Many randomised controlled trials (RCTs) have revealed the benefits of walnut on ...
Vali Musazadeh +4 more
wiley +1 more source

