Results 241 to 250 of about 214,536 (370)

Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence

open access: yesCell Proliferation, EarlyView.
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin   +21 more
wiley   +1 more source

GPD1L‐Mediated Glycerophospholipid Metabolism Dysfunction in Women With Diminished Ovarian Reserve: Insights From Pseudotargeted Metabolomic Analysis of Follicular Fluid

open access: yesCell Proliferation, EarlyView.
Our study demonstrated the downregulation of GPD1L and its mediated glycerophospholipid metabolism dysfunction in patients with diminished ovarian reserve. Moreover, we verified that GPD1L knockdown leads to increased cell apoptosis and mitochondrial dysfunction of KGN cells, as well as impaired oocyte quality.
Jiaqi Wu   +8 more
wiley   +1 more source

Clotting Factor Concentration During Menstrual Phases in Women With and Without Heavy Menstrual Bleeding: A Systematic Review and Meta‐Analysis

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Cyclic sex‐hormone fluctuation impacts clotting factor concentrations, being lowest during the follicular phase of the menstrual cycle. This pattern is unexplored in women with heavy menstrual bleeding (HMB), but potentially affects the timely diagnosis of underlying bleeding disorders.
Anne de Vaan   +5 more
wiley   +1 more source

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