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Frontiers in Endocrinology, 2019 The traditional view of follicle-stimulating hormone (FSH) as a reproductive hormone is changing. It has been shown that FSH receptors (FSHRs) are expressed in various extra-gonadal tissues and mediate the biological effects of FSH at those sites. Molecular, animal, epidemiologic, and clinical data suggest that elevated serum FSH may play a significant
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Role of FSH and FSH receptor on HUVECs migration
Gene Therapy, 2020Follicle-stimulating hormone (FSH) is a pituitary glycoprotein that regulates follicle maturation through its binding to follicle-stimulating hormone receptor (FSHR). Endothelial cells express FSHR, but its exact role in endothelial cells remains unclear. Here we show that FSHR expression was detectable in human umbilical vein endothelial cells (HUVECs)
Dailin Tan +3 more
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Polymorphism of the FSH receptor and ovarian response to FSH
Annales d'Endocrinologie, 2007Follicle-stimulating hormone (FSH) is a key factor in human reproduction. FSH activates its receptor (FSHR) located exclusively on Sertoli cells in the testis and granulosa cells in the ovary. Two common single nucleotide polymorphisms (SNP) within exon 10 of the human FSHR gene result in two almost equally common allelic variants exhibiting threonine (
WUNSCH A, SONNTAG B, SIMONI, Manuela
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FSH in the treatment of oligozoospermia
Molecular and Cellular Endocrinology, 2000The aim of this study was to individuate parameters able to distinguish oligozoospermic subjects who will respond to follicle-stimulating hormone (FSH) therapy. A group of 135 oligozoospermic subjects was divided in three groups considering basal FSH and inhibin B concentrations: group A (normal FSH and inhibin B) characterized by moderate ...
Carlo Foresta +2 more
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European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004
Infertility affects approximately 10-15% of couples. To enhance the chances of conception, assisted reproductive techniques (ART) have been improved and, in the last 5 years, thousands of babies have been delivered after IVF or ICSI procedures. To obtain an appropriate and controlled ovarian hyperstimulation (COH), clinicians have introduced many drug ...
A, Palagiano, E, Nesti, L, Pace
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Infertility affects approximately 10-15% of couples. To enhance the chances of conception, assisted reproductive techniques (ART) have been improved and, in the last 5 years, thousands of babies have been delivered after IVF or ICSI procedures. To obtain an appropriate and controlled ovarian hyperstimulation (COH), clinicians have introduced many drug ...
A, Palagiano, E, Nesti, L, Pace
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Immunoneutralization of Heterodimeric FSH Using FSH Beta Subunit as the Immunogen
American Journal of Reproductive Immunology, 1993PROBLEM: Immunization with beta subunit of gonadotropin may elicit antibody formation to endogenous heterodimeric gonadotropin and result in reproductive unresponsiveness. The objectives of this study were to determine if antibodies produced in rats following immunization with human follicle stimulating hormone beta‐subunit (hFSH‐β) could bind to and ...
G M, Butterstein, D, Sachar, J A, Dias
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Long-acting-FSH (FSH-CTP) in der Reproduktionsmedizin
Gynäkologische Endokrinologie, 2008Die ovarielle Stimulation ist integraler Bestandteil der In-vitro-Fertilisation- (IVF-)Behandlung und tragt wesentlich zur Effizienz des Verfahrens bei. Sie ist eine komplexe und haufig fur die Patientin als Belastung empfundene Modalitat der IVF-Behandlung, da sie gewohnlich die tagliche Selbstinjektion von follikelstimulierendem Hormon (FSH ...
A. Schultze-Mosgau +2 more
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Recombinant FSH versus urinary FSH
Reproductive BioMedicine Online, 2006D Caserta, R Marci, M Moscarini
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