Results 51 to 60 of about 8,757 (220)

Tissue‐level heterogeneity in FECD: Descemet's membrane phenotypes and association with TCF4 CTG18.1 expansion†

The Journal of Pathology, EarlyView.
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is commonly framed as a corneal endothelial disease characterised by guttae accumulation and progressive thickening of Descemet's membrane (DM). However, clinical forms and evolutionary profiles vary widely.
Sayo Maeno, Yoshinori Oie, Chifune Kai, Kohji Nishida   +3 more
wiley   +1 more source

Assessment of endothelial cell density and corneal thickness in corneal grafts an average of 5 years after penetrating keratoplasty [PDF]

, 2017
BACKGROUND Corneal transparency is a useful indicator for corneal function. Our aim was to investigate central corneal endothelial cells and corneal thickness in transplanted corneas at an average of 5.4 years after penetrating keratoplasty ...
Berta, András, Kemény-Beke, Ádám, Kettesy, Beáta, Módis, László, Németh, Gábor   +4 more
core   +4 more sources

Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy

Nature Communications, 2017
Fuchs endothelial corneal dystrophy (FECD) is one of the most common reasons for corneal transplantation, and is known to cluster in families. Here, the authors discover new genetic loci associated with FECD with sex-specific effects and implications for
Natalie A. Afshari, Robert P. Igo, Nathan J. Morris, Dwight Stambolian, Shiwani Sharma, V. Lakshmi Pulagam, Steven Dunn, John F. Stamler, Barbara J. Truitt, Jacqueline Rimmler, Abraham Kuot, Christopher R. Croasdale, Xuejun Qin, Kathryn P. Burdon, S. Amer Riazuddin, Richard Mills, Sonja Klebe, Mollie A. Minear, Jiagang Zhao, Elmer Balajonda, George O. Rosenwasser, Keith H Baratz, V. Vinod Mootha, Sanjay V. Patel, Simon G. Gregory, Joan E. Bailey-Wilson, Marianne O. Price, Francis W. Price, Jamie E. Craig, John H. Fingert, John D. Gottsch, Anthony J. Aldave, Gordon K. Klintworth, Jonathan H. Lass, Yi-Ju Li, Sudha K. Iyengar   +35 more
doaj   +1 more source

Endothelial dysfunction in a child with Pearson marrow-pancreas syndrome managed with Descemet stripping automated endothelial keratoplasty using a suture pull-through techniqu [PDF]

, 2019
A 4-year-old girl with a history of Pearson marrow-pancreas syndrome presenting with severe, progressive photophobia was found to have bilateral, diffuse corneal thickening and peripheral pigmentary retinopathy. She underwent Descemet stripping automated
Areaux, Raymond G., Jr., Berry, Susan, Halbach, Caroline S., Hou, Joshua H., Vadhul, Raghav   +4 more
core   +1 more source

Fuchs' Endothelial and Myotonic Dystrophies: Corneal Dystrophy in Myotonic Patients [PDF]

Investigative Opthalmology & Visual Science, 2017
n ...
De Bernardo, Maddalena, Rosa, Nicola
openaire   +3 more sources

Astigmatic changes after Descemet membrane endothelial keratoplasty (DMEK) in decompensated penetrating keratoplasty grafts

Acta Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the surgery‐induced changes of astigmatism after Descemet membrane endothelial keratoplasty (DMEK) in eyes with failed previous penetrating keratoplasty (PK). Design Retrospective, interventional cohort study based on prospective DMEK database.
Florian Thomas Steinberg, Jithmi Weliwitage, Marie von Berg, Silvia Schrittenlocher, Simona Schlereth, Claus Cursiefen, Björn Bachmann   +6 more
wiley   +1 more source

Phacoemulsification and Descemet's membrane endothelial keratoplasty in the presence of a corneal scar.

Vision Pan-America, 2015
To report the surgical outcome and visual rehabilitation  of a patient with Fuchs' dystrophy diagnosed with endothelial dysfunction associated with subepithelial and deep corneal scar and advanced cataract, treated with DMEK combined with ...
Nicolas Cesario Pereira, Aline Moiyama, Isabel Camila Amorim Gonzaga, Adriana dos Santos Forseto   +3 more
doaj   +1 more source

Génexpresszió Fuchs-dystrophiában, pseudophakiás bullosus keratopathiában és keratoconusban = Gene expression in Fuchs' dystrophy, pseudophakic bullous keratopathy and keratoconus [PDF]

, 2009
A Fuchs dystrophia (dystrophia corneae endo-, epithelialis) és a pseudophakiás bullosus keratopathia a hasonló klinikai képet mutat, mindkettő alapja a cornea endothelsejtjeinek degenerációja.
Szentmáry, Nóra, Süveges, Ildikó
core  

Sustained activation of the unfolded protein response induces cell death in Fuchs' endothelial corneal dystrophy [PDF]

, 2017
Purpose: The unfolded protein response (UPR) is believed to play a role in the pathogenesis of Fuchs' endothelial corneal dystrophy (FECD). The purpose of this study was to investigate whether unfolded proteins accumulate in the corneal endothelium in ...
Hashimoto, Keisuke, Kinoshita, Shigeru, Kitahara, Miu, Koizumi, Noriko, Kruse, Friedrich, Nakahara, Makiko, Okuda, Hirokazu, Okumura, Naoki, Quantock, Andrew J., Schlötzer-Schrehardt, Ursula, Tourtas, Theofilos, Ueda, Emi, Young, Robert D.   +12 more
core   +1 more source

SLC4A11 mutations in Fuchs endothelial corneal dystrophy [PDF]

Human Molecular Genetics, 2007
The endothelial (posterior) corneal dystrophies, which result from primary endothelial dysfunction, include Fuchs endothelial corneal dystrophy (FECD), posterior polymorphous corneal dystrophy (PPCD) and congenital hereditary endothelial dystrophy (CHED).
Vithana, E.N., Tan, D.T.H., Venkataraman, D., Venkatraman, A., Aung, T., Morgan, P.E., Casey, J.R., Ramprasad, V., Nagasamy, S., Kumaramanickevel, G., Rajagopal, R., Yam, G.H.F., Law, R.W.K., Pang, C.P., Yong, V.H.K   +14 more
openaire   +2 more sources