Results 181 to 190 of about 294,422 (268)

Household solid fuel use increases frailty risk in Chinese middle-aged and older adults: a prospective cohort study. [PDF]

Sci Rep
Liu Y, Li Z, Wu L, Ren P, Liu M, He Y, Yu Z, Liu Q, Yang J, Wang R.   +9 more
europepmc   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Heat or eat? Exploring the link between fuel poverty and diet quality among older adults aged over 50. [PDF]

Eur J Public Health
Yang H, Martin A, Dawkins B, Relton S, Howdon D.   +4 more
europepmc   +1 more source

From Pores to Pavement: Advanced Modeling of Aluminosilicates for Scalable Carbon Capture in Concrete

Advanced Science, EarlyView.
This study presents a transferable modeling framework for carbon capture using aluminosilicates, integrating Universal Isotherm Modeling with experimental data. It reveals how ultramicropores, alumina content, and amine functionalization influence CO2 adsorption energetics.
Pooja Anil Kumar Nair, Jéssica de O. N. Ribeiro, Murilo Daniel de Mello Innocentini, Kevin Paine, Juliana Calabria‐Holley   +4 more
wiley   +1 more source

Trajectory optimization for auxiliary power unit operation of an extender range electric vehicle. [PDF]

Sci Rep
Yang Y, Tian J, Jia B.
europepmc   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Effects of graphene and CNT nanoparticle additives on combustion, performance, and emissions of a diesel engine under varying injection pressures. [PDF]

Sci Rep
Raj RSN, Retnam BSJ, Anand MD, Rajan RRN, Anish M, Deepak JR, Kumar A, El-Rayyes A.   +7 more
europepmc   +1 more source

Spatial Engineering of Gas Diffusion Layers Overcomes Mass Transport Limitations in Fuel Cells

Advanced Science, EarlyView.
ABSTRACT Mass transport limitations at high current densities hinder polymer electrolyte fuel cell (PEFC) performance due to inefficient water management and reactant distribution. Gas diffusion layer (GDL) perforation offers a potential solution as an alternative to complex flow‐field modifications.
Shangwei Zhou, Wenjia Du, Jianuo Chen, Yunsong Wu, Bochen Li, Jieyang Li, Linlin Xu, Winfried Kockelmann, Meng Lin, Marc‐Olivier Coppens, Paul R Shearing, Rhodri Jervis, Thomas S. Miller   +12 more
wiley   +1 more source

A multi-criteria sustainability and engine performance study of andropogon narudus biodiesel using the PUGH matrix and ML. [PDF]

Sci Rep
Pv E, Saleel CA, Gulbarga MI, Hussain F, Khan SA, Rajendran P, Kaewthep C, Yong X.   +7 more
europepmc   +1 more source

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source