Results 121 to 130 of about 2,271,236 (350)

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

open access: yesAdvanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal   +3 more
wiley   +1 more source

A review of developments in electrodes for regenerative polymer electrolyte fuel cells

open access: yes, 2006
The design of electrodes for unitised regenerative polymer electrolyte fuel cells (URFC) requires a delicate balancing of transport media. Gas transport, electrons and protons must be carefully optimised to provide efficient transport to and from the ...
Pettersson, J, Harrison, DJ, Ramsey, BJ
core  

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Investigating the Effect of Engine Lubricant Viscosity on Engine Friction and Fuel Economy of a Diesel Engine

open access: yes
Fuel economy is affected, both by fuel and engine lubricant quality. Engine lubricant quality plays a vital role in reduction of fuel consumption by effective reduction of friction between the contact surfaces of engine parts (piston ring assembly ...
Singh, Devendra
core  

Assessment of helical-cruciform fuel rods for high power density

open access: yes, 2010
In order to significantly increase the power density of Light Water Reactors (LWRs), the helical-cruciform (HC) fuel rod assembly has been proposed as an alternative to traditional fuel geometry.
McKrell, Thomas J.   +2 more
core  

Spatial Engineering of Gas Diffusion Layers Overcomes Mass Transport Limitations in Fuel Cells

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mass transport limitations at high current densities hinder polymer electrolyte fuel cell (PEFC) performance due to inefficient water management and reactant distribution. Gas diffusion layer (GDL) perforation offers a potential solution as an alternative to complex flow‐field modifications.
Shangwei Zhou   +12 more
wiley   +1 more source

Optimization of the LWR Nuclear Fuel Cycle for Minimum Waste Production

open access: yes, 2003
The once through nuclear fuel cycle adopted by the majority of countries with operating commercial power reactors imposes a number of concerns. The radioactive waste created in the once through nuclear fuel cycle has to be isolated from the environment
Kazimi, Mujid S.   +2 more
core  

Analysis of Transverse Flow Characteristics in LBE-cooled Wire-wrapped Fuel Assembly

open access: yesYuanzineng kexue jishu, 2022
LBE-cooled fast reactor (LBFR) has a promising application prospect in energy generation and transmutation of highlevel radioactive waste. Wirewrapped fuel rods are usually used in LBFR to reach high heat transfer efficiency and selfsupport.
CONG Tenglong;WANG Junjie;XIAO Yao;LIU Maolong;GU Hanyang
doaj  

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

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