Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Insights Into Atomic Ordering and Morphological Control Integration Design for Next-Generation Proton Exchange Membrane Fuel Cells. [PDF]
Lee E, Baik J, Kang JS, Yoo SJ.
europepmc +1 more source
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang +10 more
wiley +1 more source
Microbial fuel cells for wastewater treatment and electricity production: A multi-platform simulation workflow. [PDF]
Ali M.
europepmc +1 more source
Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng +10 more
wiley +1 more source
Assessment of a modified Coronavirus Disease Optimization Algorithm for Parameter Estimation of Proton Exchange Membrane Fuel Cells. [PDF]
Ismaeel AAK +6 more
europepmc +1 more source
Spatial Engineering of Gas Diffusion Layers Overcomes Mass Transport Limitations in Fuel Cells
ABSTRACT Mass transport limitations at high current densities hinder polymer electrolyte fuel cell (PEFC) performance due to inefficient water management and reactant distribution. Gas diffusion layer (GDL) perforation offers a potential solution as an alternative to complex flow‐field modifications.
Shangwei Zhou +12 more
wiley +1 more source
Modeling of solid oxide fuel cells and optimal parameter extraction at various operating data using an optimization method. [PDF]
Abaza A +4 more
europepmc +1 more source

