Results 61 to 70 of about 2,950,028 (313)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

An Approach for Predicting the Specific Fuel Consumption of Dual-Fuel Two-Stroke Marine Engines

Journal of Marine Science and Engineering, 2019
Increasing environmental demands, alongside the planned penetration of natural gas as marine fuel, have rendered dual-fuel engines as an attractive prime mover alternative.
Crístofer H. Marques, Jean-D. Caprace, Carlos R. P. Belchior, Alberto Martini   +3 more
doaj   +1 more source

Interaction of class III cellobiose dehydrogenase with lytic polysaccharide monooxygenase

FEBS Open Bio, EarlyView.
The activity of lytic polysaccharide monooxygenase (LPMO) is supported by its auxiliary enzyme cellobiose dehydrogenase (CDH). The catalytic activity of both enzymes is coupled by electron transfer and a cyclic cascade generating substrates for both enzymes – hydrogen peroxide for LPMO and oxidized and non‐oxidized cellobiose and cello‐oligosaccharide ...
Angela Giorgianni, Florian Csarman, Peicheng Sun, Mirjam Kabel, Roland Ludwig   +4 more
wiley   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

Advanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani, Surabhi Nadigotti, Erfan Fatehi, Derek Aranguren van Egmond, Behnam Ashrafi   +4 more
wiley   +1 more source

Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review

Advanced Engineering Materials, EarlyView.
Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang, Hanliang Zhu, Zhiyang Wang, Zhijun Qiu, Xiao Wang, Zengxi Pan, Hongtao Zhu, Mingxing Zhang, Huijun Li   +8 more
wiley   +1 more source

A Vehicle Fuel Consumption Model on Reconstructed Roads Based on the Roughness and Its Measurement Method

Advances in Civil Engineering, 2021
The fuel consumption model for a vehicle forms a basis and method for evaluating the social benefit of road reconstruction. Based on the theoretical fuel consumption model of vehicles, the influence mechanism of the apparent parameters of the road ...
Qiang Liu, Jianguang Xie, Zhixiang Zhang
doaj   +1 more source

Titanium‐S23: A New Alloy with Ultra‐High Tensile Toughness Directly from the Solid‐State Processing of Recycled Ti–6Al–4V and Ti–5Al–5Mo–5V–3Cr Powders using Field Assisted Sintering Technology

Advanced Engineering Materials, EarlyView.
This study explores combining two existing aerospace titanium alloy powders, processing them via field‐assisted sintering technology and the subsequent discovery of a novel alloy composition, termed S23, with ultra‐high tensile toughness. Fine‐scale alpha precipitates favorably form in the alloy despite the relatively slow cooling, providing an ...
Samuel Lister, Gavin J. Baxter, Martin Jackson   +2 more
wiley   +1 more source

Simulation Research on Fuel Temperature Variation Law of a UAV during Climbing

Hangkong gongcheng jinzhan, 2021
The medium altitude long endurance UAV Using RON 95# vehicle gasoline or 100LL aviation gasoline as fuel is prone to encounter air lock during climbing. The simulation model of the UAV fuel system is built by using the Flowmaster software.
WEN Zhanyong
doaj   +1 more source

Nano‐Patterned CuO Nanowire Nanogap Hydrogen Gas Sensor with Voids

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
Sub‐5‐ppb hydrogen (H2) detection and sub‐10‐s response and recovery times are achieved based on nano‐patterned polycrystalline CuO nanowires nanogap gas sensors with voids using electron‐beam lithography and unique annealing processes. Pre‐H2 annealing, void‐generating oxidation, and downscaled nanogap electrodes are key to improving the sensing ...
Muqing Zhao, Ryosuke Nitta, Seiichiro Izawa, Jun‐ichi Yamaura, Yutaka Majima   +4 more
wiley   +1 more source