Results 31 to 40 of about 151,822 (266)

Approaches to simulate destruction of a fuel rod with different fuel types

Journal of Physics: Conference Series, 2020
Abstract Due to the revival of interest to the development of fast reactors cooled by liquid metals, the theoretical research for improving their safety is actual. A detailed calculation of all stages of an accident from the beginning to the end requires knowledge of the laws for modelling physical processes occurring in the reactor in ...
E V Usov, A R Gafiyatullin, I A Klimonov, V I Chuhno   +3 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A LiDAR signature library simulated from 3-dimensional Discrete Anisotropic Radiative Transfer (DART) model to classify fuel types using spectral matching algorithms

GIScience & Remote Sensing, 2019
Fuel types are one of the key variables that drive wildfire ignition and propagation. A new method is proposed to automatically classify and map fuel types from LiDAR data.
M. Teresa Lamelas-Gracia, David Riaño, Susan Ustin   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Modification of Neutron Kinetic Code for Plate Type Fuel Nuclear Reactor

Science and Technology of Nuclear Installations, 2013
The research is conducted on the modification of neutron kinetic code for the plate type fuel nuclear reactor. REMARK is a neutron kinetic code that works only for the cylindrical type fuel nuclear reactor.
Salah Ud-Din Khan, Shahab Ud-Din Khan, Yang Zhifei   +2 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Monitoring Wildfire Risk with a Near-Real-Time Live Fuel Moisture Content System: A Review and Roadmap for Operational Application in New Zealand

Remote Sensing
Live fuel moisture content (LFMC) is a critical variable influencing wildfire behavior, ignition potential, and suppression difficulty, yet it remains challenging to monitor consistently across landscapes due to sparse field observations, rapid temporal ...
Michael S. Watt, Shana Gross, John Keithley Difuntorum, Jessica L. McCarty, H. Grant Pearce, Jacquelyn K. Shuman, Marta Yebra   +6 more
doaj   +1 more source

Energy audit and carbon footprint in trawl fisheries

Scientific Data, 2022
Measurement(s) vessel speed • latitude • longitude • fuel consumption • shaft rotational speed • shaft torque • fishing gear drag  Technology Type(s) GPS navigation system • mass and volumetric flow meter • shaft power measurement system with optical ...
Antonello Sala, Dimitrios Damalas, Lucio Labanchi, Jann Martinsohn, Fabrizio Moro, Rosaria Sabatella, Emilio Notti   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source