Results 141 to 150 of about 314,216 (251)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Propuesta de un modelo para el aprendizaje de hábitos posturales en la escuela

open access: yesRECUS, 2016
Entre  los  factores  ambientales  que  influyen  en  las  alteraciones osteomusculares  del niño son las posturas inadecuadas durante el sueño,  el  tiempo  de  juego  y  como  se  sienta1.
Edgar Ramiro Monroy
doaj  

What Drives the Current Account in Commodity Exporting Countries? The Cases of Chile and New Zealand [PDF]

open access: yes
This paper uses an open economy DSGE model with a commodity sector and nominal and real rigidities to ask what factors account for current account developments in two small commodity exporting countries.
Anella Munro   +2 more
core  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Choosing an Exchange Rate Regime [PDF]

open access: yes
Choosing an exchange rate regime is one of the most important decisions in macroeconomic policymaking. Some countries may peg their currency to gain credibility and control domestic inflation, while others may be more prone to float due to the larger ...
César Calderón, Klaus Schmidt Hebbel
core  

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Evapotranspiración y coeficientes de cultivo (Kc) de stevia [Stevia rebaudiana (Bertoni) Bertoni] bajo condiciones parcialmente protegidas

open access: yesBioagro
La evapotranspiración de referencia (ETo) de una zona y el coeficiente del cultivo (Kc) representan parámetros necesarios para determinar los requerimientos hídricos de las plantas. El objetivo de este estudio fue determinar la tasa de evapotranspiración
Gustavo Villafañe   +2 more
doaj  

On The Removal of Agricultural Price Bands in Chile: A General Equilibrium Analysis [PDF]

open access: yes
Chile has supported its agriculture with the use of price bands on selected commodities namely wheat, vegetable oils and fats, and sugar. In this paper we consider agricultural reform and how urban unemployment, and rural-urban migration, may alter the ...
David Holland   +3 more
core  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

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