Results 51 to 60 of about 314,216 (251)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Publicaciones e Investigación, 2018 Los servicios logísticos prestados en el sector industrial, a nivel nacional e internacional, han presentado un balance positivo y relevancia en el dinamismo del sector productivo.
Gustavo A Araque +3 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Acta Agronómica, 2018 Se reconoce que el ambiente térmico es uno de los factores ecológicos más importantes para determinar el crecimiento, el desarrollo y la productividad de animales domésticos con efectos directos e indirectos sobre su fisiología y comportamiento.
Raúl Andrés Molina Benavides +2 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Capacidad de infiltración de la cuenca del río Cuxtepeques, Chiapas, México
Ingeniería Hidráulica y Ambiental, 2016 La reserva de la biosfera El Triunfo (REBITRI) es un importante regulador hídrico de corrientes que alimentan diversas cuencas de México. A pesar de ello, los servicios ecosistémicos que proporciona son poco valorados.
Walter López Báez +4 more
doaj
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
La izquierda chilena contemparánea
Revista Mexicana de Ciencias Políticas y Sociales, 2006 En este artículo, el autor examina las particularidades de la izquierda chilena para entender su papel en los gobiernos democráticos desde los años 70.
Manuel Antonio Garretón
doaj
Revista de la Asociación Argentina de Ortopedia y Traumatología, 2012 Introducción El éxito a largo plazo de un reemplazo total de rodilla (RTR) depende de la restitución del eje mecánico del miembro, de la correcta colocación del implante y del balance de partes blandas.
Hernan del Sel +4 more
doaj +1 more source