Results 71 to 80 of about 314,216 (251)

El papel de la emigración en la situación socioeconómica de Ecuador [PDF]

open access: yes, 2011
Ecuador es un país en vías de desarrollo con una balanza de pagos anual que actualmente consigue equilibrar en cierta medida gracias al sector petrolífero y a las remesas económicas de los emigrantes; con la caída de alguno de estos dos pilares, la ...
Martínez Hernández, Carlos
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Financial Frictions and Real Devaluations [PDF]

open access: yes
In this paper I study the effects of real exchange rate devaluations on output performance using a sample of large devaluation episodes for a group of emerging and developed countries.
Alvaro Aguirre, César Calderón
core  

Relation between source and temperature fluctuations in photoionized nebulae [PDF]

open access: yes, 2003
The magnitude of the temperature fluctuations (t^2) required to explain the observed inconsistencies between metallicities inferred from recombination lines and from forbidden lines cannot be attained by steady-state equilibrium photoionization models ...
Binette, Luc   +3 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

La versión no institucionalizada de la creación de la Ruta Turística Don Vasco de Michoacán, México

open access: yesPensamiento y Acción Interdisciplinaria
En la presente investigación se analizó el caso de la versión histórica no oficial o institucionalizada de cómo fue que nació la Ruta Turística Don Vasco, del estado de Michoacán, México, con el objetivo de mostrar que no sólo es vital efectuar estudios
Brisol García
doaj   +1 more source

The Optimal Inflation Tax in the Presence of Imperfect Deposit – Currency Substitution [PDF]

open access: yes
During the last decades, technological innovation has generated a major transformation in payment systems, stimulating a widespread use of different forms of electronic money and increasing substitutability between deposits and currency in transactions ...
Eduardo Olaberría
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Must Original Sin Cause Macroeconomic Damnation? [PDF]

open access: yes
Original sin, coupled with other financial imperfections, causes macroeconomic penance of two kinds: adverse shocks have larger and more persistent effects and monetary policy becomes less effective as a shock absorber. But macroeconomic damnation is not
Andrés Velasco   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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