Introduction and aims: Esophagectomy is a highly invasive surgery and one of its postoperative complications is anastomotic leakage, occurring in 53% of cases. The aim of the present study was to determine the sensitivity of the contrast-enhanced swallow
S. Mejía-Rivera +3 more
doaj +2 more sources
Meta-analysis of the impact of postoperative infective complications on oncological outcomes in colorectal cancer surgery. [PDF]
Postoperative infective complications have significant negative effects on oncological outcomes in colorectal cancer. Anastomotic leakage has a negative effect on every measured outcome. New registries should include oncological outcomes and complications to facilitate future research and optimize outcomes.
Lawler J +5 more
europepmc +2 more sources
Stoma reversal after intended restorative rectal cancer resection in Denmark: nationwide population-based study. [PDF]
In this Danish population‐based cohort study, the stoma reversal rate during 3 years of follow‐up was estimated among patients undergoing intended restorative rectal cancer resection, and characteristics predictive of stoma reversal were explored. One‐quarter of patients had not had their diverting stoma reversed, and more than one‐half of patients ...
Jørgensen JB +4 more
europepmc +2 more sources
Value of individual surgeon performance metrics as quality assurance measures in oesophagogastric cancer surgery. [PDF]
Annual surgeon‐level metrics demonstrated the greatest variation (fivefold) risking inappropriate target thresholds. Surgeon‐level performance metrics were not associated with survival, suggesting that compound‐level quality assurance provides better overall performance appraisal.
Powell AGMT +7 more
europepmc +2 more sources
Anastomotic leakage after elective colorectal surgery: a prospective multicentre observational study on use of the Dutch leakage score, serum procalcitonin and serum C-reactive protein for diagnosis. [PDF]
Early diagnosis and treatment of anastomotic leakage (AL) is crucial to limit related mortality. In this prospective 1‐year multicentre study of 1546 patients who had an elective colorectal resection with anastomosis, the AL rate was 4·9 per cent. The Dutch leakage score was the best predictor of AL on days 2 and 3 after surgery. Colorectal surgery and
Italian ColoRectal Anastomotic Leakage (iCral) Study Group.
europepmc +2 more sources
Locoregional recurrences after transanal total mesorectal excision of rectal cancer during implementation. [PDF]
During the learning curve, the transanal total mesorectal excision procedure is associated with a high multifocal local recurrence rate, which appears to be related to suboptimal execution rather than the technique, and necessitates prolonged proctoring, optimization of the technique avoiding spillage, participation in controlled clinical trials with ...
van Oostendorp SE +21 more
europepmc +2 more sources
Minimally invasive techniques for transthoracic oesophagectomy for oesophageal cancer: systematic review and network meta-analysis. [PDF]
Minimally invasive and robotic techniques for oesophagectomy are associated with reduced perioperative morbidity and length of hospital stay, with no compromise of oncological outcomes but no improvement in perioperative mortality. There are suggestions of improved long‐term survival with minimally invasive oesophagectomy and robotic minimally invasive
Siaw-Acheampong K +5 more
europepmc +2 more sources
Effect of oxygen-producing suture material on hypoxic colonic anastomoses in an experimental model. [PDF]
Anastomotic leak remains a significant problem after colorectal surgery, and administration of supplemental perioperative oxygen has been shown to improve healing of colorectal anastomoses. The manufacture of an oxygen‐producing suture material is described; experiments showed that it improved some aspects of the healing of bowel anastomoses.
Inglin RA +4 more
europepmc +2 more sources
This study demonstrates that anastomotic leakage leads to prolonged critical care and in‐hospital stay, and is associated with compromised long‐term overall survival. Future research should aim at developing mechanisms and interventions to reduce the risk of anastomotic leaks. Leaks impair outcomes Background The impact of anastomotic leak (AL) on long‐
S. K. Kamarajah +3 more
wiley +1 more source
Valoración inmunológica en la detección de la infección perioperatoria en pacientes intervenidos por cáncer de colon [PDF]
Objetivos: Evaluar la utilidad de la cuantificación en la concentración de leucocitos y subpoblaciones linfocitarias en sangre para identificar la presencia de fuga anastomótica, en pacientes intervenidos de cáncer de colon, incluso antes de la aparición
Moreno Racionero, Francisca +6 more
core +3 more sources

