Results 71 to 80 of about 676,375 (253)

Advances in full-color MicroLED micro-display technology

Nantong Daxue xuebao. Ziran kexue ban
The widespread application and popularization of novel display products such as wearable devices, augmented reality(AR), and mixed reality(MR) have imposed higher performance requirements on new display technologies,particularly in terms of ...
YAN Long; HAN Bing; ZHAO Xiangjie; HUANG Jianhua; TONG Yang; LI Ziwei
doaj   +1 more source

Polarization-encrypted high-resolution full-color images exploiting hydrogenated amorphous silicon nanogratings

Nanophotonics, 2020
As a prominent alternative to toxic dyes/pigments, nanostructural color pixels have garnered tremendous attention in applications related to display/imaging devices and color printings.
Yue Wenjing, Gao Song, Li Yang, Zhang Chunwei, Fu Xiaoqian, Choi Duk-Yong   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

An all-photonic full color RGB system based on molecular photoswitches

Nature Communications, 2019
Stimuli-responsive multicolor luminescent materials typically react on external triggers of physical nature, but photonically controlled systems which allow for remote operation were not realized.
Gaowa Naren, Chien-Wei Hsu, Shiming Li, Masakazu Morimoto, Sicheng Tang, Jordi Hernando, Gonzalo Guirado, Masahiro Irie, Françisco M. Raymo, Henrik Sundén, Joakim Andréasson   +10 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Palm-Sized Single-Shot Full-Color Incoherent Digital Holographic Camera System with White Light

Advanced Devices & Instrumentation
The realization of full-color motion-picture holographic imaging with daily-use light is an important research objective. To achieve it, various types of single-shot phase-shifting incoherent digital holography (SSPS IDH) systems have been proposed up to
Tatsuki Tahara, Tomoyoshi Shimobaba
doaj   +1 more source

High Brightness Full Color LEDs.

Journal of Light & Visual Environment, 1999
A new Multi-Layer type full color LED, capable of mixing different luminous wavelengths to radiate many different colors of light (visible also from a short distance), at high levels of efficacy. Excellent luminous intensity, has been demonstrated by the prototype.
SUEHIRO, Yoshinobu, SATO, Takashi, UCHIDA, Koji, YAMAZAKI, Shigeru   +3 more
openaire   +2 more sources