Results 201 to 210 of about 2,779,069 (311)

Intelligent cloud-based RAS management: integration of DDPG reinforcement learning with AWS IoT for optimized aquaculture production. [PDF]

Sci Rep
Elmessery WM, Shams MY, El-Hafeez TA, Eid MH, Székács A, Saeed O, Ahmed AF, Alhumedi M, Elwakeel AE.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Digital Intervention for Capturing Real-Time Health Data for Epilepsy Seizure Forecasting: Protocol for the ATMOSPHERE Study.

JMIR Res Protoc
Thompson L, Nielsen E, Quilter EEV, Slay A, Wac M, Wragg M, Downes S, Tittensor P, Junges L, Stuart L, Charles R, Kissack P, Qureshi Y, Brigden A.   +13 more
europepmc   +1 more source

Posttraumatic cerebrospinal fluid leak with cognitive dysfunction, especially visual memory disturbance: illustrative case. [PDF]

J Neurosurg Case Lessons
Suzuki K, Matsuda T, Hara K, Nakamura K, Kuno M, Miyake K, Korai M, Sato N, Matsuura T, Takagi Y.   +9 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Experimental data of charring of timber elements under natural fire: Full-scale fire testing of timber structures using the room corner test method. [PDF]

Data Brief
Šejna J, Štraus D, Křišťanová M, Rušarová S, Cábová K, Pečenko R, Hozjan T, Wald F.   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Study on the Performance Enhancement Mechanism of Basalt Fiber-Reinforced Hydraulic Concrete in Ship Lock Galleries. [PDF]

Materials (Basel)
Lu B, Chen J, Xiang S, Peng Z, Liu C, Li L.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Assessment of Masticatory Performance: A Systematic Review of Current Assessment Methods and Measurement Properties. [PDF]

Int Dent J
Khaing AMM, Maung MM, Maung EM, Khant W.
europepmc   +1 more source