Results 61 to 70 of about 15,783 (244)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Full-Bridge Intermediate-Frequency Converter with Low Voltage and Current Stress on Auxiliary Switching Devices

open access: yesEnergies
The DC converter constitutes a pivotal component within medium-voltage direct current (MVDC) collection systems, performing functions such as voltage boosting, isolation, and power transmission.
Shilong Gao   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Energy Management and Control Strategy of Photovoltaic/Battery Hybrid Distributed Power Generation Systems With an Integrated Three-Port Power Converter

open access: yesIEEE Access, 2019
Photovoltaic (PV)/battery hybrid power units have attracted vast research interests in recent years. For the conventional distributed power generation systems with PV/battery hybrid power units, two independent power converters, including a ...
Jiatu Hong   +4 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Critical Clearing Time and Wind Power in Small Isolated Power Systems Considering Inertia Emulation

open access: yesEnergies, 2015
The stability and security of small and isolated power systems can be compromised when large amounts of wind power enter them. Wind power integration depends on such factors as power generation capacity, conventional generation technology or grid ...
Elías Jesús Medina-Domínguez   +1 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

High Frequency High Power Full Bridge Converter for Plasma Torches

open access: yesJournal of Physics: Conference Series, 2017
© Published under licence by IOP Publishing Ltd.This paper presents a full bridge converter with a high speed rectifier and filter for plasma torches. Full bridge circuit with high frequency pulse width modulation control is used and high frequency transformer to insulate is adopted.
Hakki A., Sadikov K., Kashapov N.
openaire   +3 more sources

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