Results 191 to 200 of about 9,794,120 (297)

Machine learning vs. ADM1: Reliable biogas prediction with minimal data requirements in full-scale plants. [PDF]

Environ Sci Ecotechnol
Tisocco S, Weinrich S, Møller HB, Ward AJ, Kilmartin L, Zhan X, Crosson P.   +6 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Fs2PA: A Full-Scale Feature Synergistic Perception Architecture for Vehicular Infrared Object Detection via Physical Priors and Semantic Constraints. [PDF]

Sensors (Basel)
Pei B, Wu L, Zheng X, Zhou C, Wang D.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Full-scale slurry tank sampling: Effects of sampling strategy and sample storage on measured physical and chemical properties. [PDF]

J Environ Qual
Kamp JN, Sørensen MK, Pedersen J.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Verification of the Applicability of the FAD Method Based on Full-Scale Pressurised Tensile Tests of Large-Diameter X80 Pipelines. [PDF]

Materials (Basel)
Chen X, Zhen Y, Zheng H, Jin H, Hang R, Guo X, Xiao J, Zhou H.   +7 more
europepmc   +1 more source

Optimal Design and Experimental Verification of a Full-Scale Composite Rotor Blade with Macro-Fiber Composite Actuators

The aim of the present work is development of an active twist actuation concept for a reduction of vibration and blade-vortex interaction (BVI) noise of helicopters to improve their overall performance.
Kovaļovs, Andrejs, Gluhih, Sergejs, Barkanovs, Jevgenijs   +2 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

CAU-10-H: Synthesis Scale-Up at the Pilot Scale, Techno-Economic Analysis, and Application in a Full-Scale Cooling System. [PDF]

Ind Eng Chem Res
Mertin KS, Mohtar A, Bordonhos M, Pinto ML, May T, Herrmann R, Stock N.   +6 more
europepmc   +1 more source