Results 91 to 100 of about 1,711,763 (306)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Journal of Intelligence, 2017 Evidence suggests that cytokines may be one of the major factors influencing cognitive development in those with autism spectrum disorder (ASD). To shed light on the neural and cognitive mechanisms of ASD, we investigated the association between ...
Daimei Sasayama +9 more
doaj +1 more source
Fatigue experience from tests carried out with forged beam and frame structures in the development of the Saab aircraft Viggen [PDF]
A part of the lower side of the main wing at the joint of the main spar with the fuselage frame was investigated. This wing beam area was simulated by a test specimen consisting of a spar boom of AZ 74 forging (7075 aluminum alloy modified with 0.3 ...
Larsson, S. E.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
AerospaceThe main purpose of this study comprises the design and the development of a novel experimental configuration for carrying out tests on a full-scale stiffened panel manufactured of fiber-reinforced thermoplastic material.
Panagiotis D. Kordas +2 more
doaj +1 more source
Size and Scale Economies in Japanese Cooperative Banking [PDF]
The Japanese banking industry, including the cooperative sector has been restructured following the crisis of the 1990s. Here we examine the relationship between size and scale economies of cooperative banks in Japan (namely Shinkin and credit ...
Carol Padgett, Tara Deelchand
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Case Studies in Thermal EngineeringThis study introduces a novel integrated methodology combining wind tunnel (WT) experiments, Computational Fluid Dynamics (CFD), and Finite Element Analysis (FEA) to thoroughly evaluate wind-induced effects on ground-mounted photovoltaic (PV) tracking ...
Krishna Debnath +6 more
doaj +1 more source
Flight service evaluation of composite helicopter components [PDF]
An assessment of composite helicopter structures, exposed to environmental effects, after four years of commercial service is presented. This assessment is supported by test results of helicopter components and test panels which have been exposed to ...
Lowry, D. W., Rich, M. J.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source