Microbial Virulence Factors [PDF]
, 2021 Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease.
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Purification, formulation and characterisation of the adenylate cyclase toxin of Bordetella pertussis [PDF]
, 2006 Adenylate cyclase toxin (CyaA) toxin is an important virulence factor of Bordetella pertussis, the causative agent of whooping cough, and a potential component of acellular pertussis vaccine.
Khosravani, Abdolmajid
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Biochemical characterization of monoclonal antibodies to the Bordetella pertussis Filamentous hemagglutinin (FHA) and Pertussis toxin (PTx) : implications for improved acellular pertussis vaccine design [PDF]
, 2017 Incidence rates of whooping cough were dramatically decreased by immunization with whole cell pertussis (wP) vaccines in the 1940s. However, concerns about the safety of the wP vaccine resulted in development of new pertussis vaccines using acellular ...
Acquaye, Edith Abena
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Investigation of Key Mechanisms of Contact Dependent Growth Inhibition Systems in \u3ci\u3eBurkholderia cepacia\u3c/i\u3e Complex Species [PDF]
, 2023 Burkholderia cepacia complex is a group of closely related environmental bacteria that can exacerbate disease in immunocompromised individuals. B. cepacia bacteria are equipped with an arsenal of mechanisms to cooperate and compete for nutrients in ...
Elery, Zaria K.
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Approaches to New Generation Vaccines against Pertussis and Identification of Virulence Factors [PDF]
, 2017 Despite high vaccination coverage world-wide, whooping cough, a highly contagious disease caused by Bordetella pertussis, is recently increasing in occurrence suggesting that novel vaccine formulations targeted at the prevention of colonization and ...
Gasperini, Gianmarco <1989>
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Enhancement of Immune Response Against Bordetella spp. by Disrupting Immunomodulation [PDF]
, 2019 Well-adapted pathogens must evade clearance by the host immune system and the study of how they do this has revealed myriad complex strategies and mechanisms.
Barbier, Mariette +10 more
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Spatiotemporal Control of Mycobacterium Tuberculosis Cell Wall Biogenesis by the Peptidoglycan Synthase PonA1 [PDF]
, 2015 Mycobacterium tuberculosis causes one of the most pernicious infectious diseases of humankind – tuberculosis, which is still a global problem in the 21st century. Drug-resistant M.
Kieser, Karen Jane
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Involvement of Fimbriae in attachment by Bordetella Bronchiseptica [PDF]
, 1995 Bordetella bronchiseptica is a Gram negative respiratory tract pathogen which infects a wide variety of animal species including dogs, pigs, and guinea pigs. Infection and colonization of ciliated respiratory epithelial cells by B.
Burns, Eugene Hugh
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The immunomodulatory and cytotoxic effects of different forms of recombinant adenylate cyclase toxin [PDF]
, 2006 This thesis describes the small- and large-scale purification of four different recombinant forms of CyaA, namely; fully functional enzymically-active, acylated and invasive CyaA; an acylated and invasive CyaA form lacking adenylate cyclase (AC) enzymic ...
Cheung, Yiu Chong Gordon
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Functional analyses of pSer and pThr binding domains [PDF]
, 2013 Since the discovery of the phosphotyrosine binding SH2 domain, many classes of phospho-recognition domains have been described which mediate many of the diverse cellular functions of protein kinases.
Stach, L
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