Characterization of LYTM domain containing proteins in mycobacterium smegmatis [PDF]
, 2017 A dissertation submitted to the Faculty of Health Science, University of the Witwatersrand, Johannesburg, in fulfillment of the requirements for the degree of Master of Science in Medicine.
Shaku, Tube Moagi
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FHA-mediated cell-substrate and cell-cell adhesions are critical for Bordetella pertussis biofilm formation on abiotic surfaces and in the mouse nose and the trachea [PDF]
, 2013 Bordetella spp. form biofilms in the mouse nasopharynx, thereby providing a potential mechanism for establishing chronic infections in humans and animals. Filamentous hemagglutinin (FHA) is a major virulence factor of B. pertussis, the causative agent of
Arnal, Laura +6 more
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The protective and immunomodulatory properties of Bordetella pertussis adenylate cyclase toxin [PDF]
, 2002 Bordetella pertussis is the causative agent of the disease whooping cough in man, and although there is an effective whole-cell vaccine (WCV), recent efforts have focused on the development of the acellular vaccines (ACVs) to avoid the problems of ...
MacDonald-Fyall, Julia
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Characterization of mycobacterial peptidoglycan remodelling enzymes [PDF]
, 2018 A dissertation submitted to the Faculty of Health Science, University of the Witwatersrand, Johannesburg, in fulfillment of the requirements for the degree of Master of Science in Medicine.
Mashilo, Poppy
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Functional analysis of the serine-threonine protein kinase PknF and its substrate, the ABC transporter Rv1747, in Mycobacterium tuberculosis [PDF]
, 2011 Mycobacterium tuberculosis, the causative agent of tuberculosis exists in a number of different environmental states. It must therefore have gene regulatory systems which are specific for virulence.
Spivey, V.L.
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Sorting Signals of Borrelia Lipoproteins [PDF]
, 2009 Bacterial lipoproteins play important roles in prokaryotic physiology, protein transport, membrane biogenesis, and pathogenesis. Produced in the cytoplasm, these proteins are N-terminally modified by the covalent addition of a fatty-acid moiety onto a ...
Schulze, Ryan Joseph
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Signalizační působení adenylát-cyklázového toxinu na fagocyty [PDF]
, 2016 Adenylát-cyklázový toxin (CyaA) je klíčovým faktorem virulence bakterie Bordetella pertussis. CyaA se váže na fagocyty produkující komplementový receptor 3 (CR3) a následně katalyzuje přeměnu vnitrobuněčného ATP na významného "druhého posla" cAMP.
Černý, Ondřej
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Estudio de un brote epidémico causado por distintas cepas de "Acinetobacter baumannii" multirresistente: estudio de la epidemicidad y virulencia [PDF]
, 2015 Programa Oficial de Doutoramento en Ciencias da Saúde. 5007V01[Resumen] El patógenos oportunista Acinetobacter baumannii es uno de los seis microorganismos multirresistentes que más preocupa en hospitales de todo el mundo.
Merino Carballeira, María
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Next generation approaches to polysaccharide preparation for Burkholderia pseudomallei vaccine development. [PDF]
, 2016 Burkholderia pseudomallei is the aetiological agent of melioidosis and a potential bioterror threat. Infections are difficult to treat due to extensive antibiotic resistance and there is no prophylactic vaccine available.
Baldwin, Victoria Mae
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Immune responses of calves after vaccination with a live attenuated derivative of Pasteurella multocida B:2 [PDF]
, 2007 The primary aim of this research was to investigate safety and potency of an aroA mutant of Pasteurella multocida serotype B:2 (JRMT12) as a live vaccine candidate in cattle against experimental haemorrhagic septicaemia (HS).
Kachooei, Saeed Ataei
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