Results 91 to 100 of about 3,547 (202)
Mutation of H63 and its Catalytic Affect on the Methionine Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 2009 In order to gain insight into the mechanistic role of a flexible exterior loop near the active site, made up of Y62, H63, G64, and Y65, that has been proposed to play an important role in substrate binding and recognition in the methionyl aminopeptidase ...
Bennett, Brian +2 more
core +2 more sources
Mutant methionyl-tRNA synthetase from bacteria enables site-selective N-terminal labeling of proteins expressed in mammalian cells [PDF]
, 2013 Newly synthesized cellular proteins can be tagged with a variety of metabolic labels that distinguish them from preexisting proteins and allow them to be identified and tracked.
Ngo, John T. +2 more
core +2 more sources
Chemoproteomics, A Broad Avenue to Target Deconvolution
Advanced Science, Volume 11, Issue 8, February 23, 2024.Striving to identify the molecular targets of a bioactive compound, target deconvolution acts as the link between phenotypic chemical screening and comprehensive exploration of the underlying mechanisms. Various chemoproteomic approaches, facilitated by chemical probe‐assisted target enrichment or probe‐free methodologies, have been developed and ...
Yihui Gao +3 more
wiley +1 more source
Complexity of fungal polyketide biosynthesis and function
Molecular Microbiology, Volume 121, Issue 1, Page 18-25, January 2024.Fungal secondary metabolites are the basis of many pharmaceuticals. Fungal genome analyses revealed a huge, but yet unexplored potential for more and new secondary metabolites. The review focuses on polyketides, their biosynthesis, their natural functions, and strategies for new discoveries of compounds and functions.
Maria C. Stroe +3 more
wiley +1 more source
Science Journal of University of Zakho, 2013 Cytogenetic effects of honey contaminated with fumagillin that collected from different sources in Duhok province was investigated in mouse bone-marrow cells using damaged cells%, (chromatids and chromosomal aberrations and mitotic index (M.I).
Soleen Sardar Zuhdi +1 more
doaj
mBio, 2020 G-protein coupled receptors (GPCRs) are extracellular signaling receptors that sense environmental cues. Fungi sense their environment primarily through GPCR-mediated signaling pathways, which, in turn, regulate fungal development, metabolism, virulence,
Aílton Pereira da Costa Filho +16 more
doaj +1 more source
Bone growth following demineralized bone matrix implantation requires angiogenesis [PDF]
, 2016 Angiogenesis is required for endochondral ossification during development and fracture healing; however the exact mechanisms and temporal relationship between the two processes remains unclear.
Lam, Stephanie
core
International Journal of Analytical Chemistry, Volume 2024, Issue 1, 2024.It has been well‐established that mycotoxins are poisonous chemical metabolites secreted by certain molds. Some of them significantly affect the health of humans and livestock. Increasing attention is now being paid to uncovering and identifying mycotoxins’ presence in the building’s environment.
Salina Abdul Rahman +6 more
wiley +1 more source
Anticancer and antifungal compounds from Aspergillus, Penicillium and other filamentous fungi [PDF]
, 2013 This review covers important anticancer and antifungal compounds reported from filamentous fungi and in particular from Aspergillus, Penicillium and Talaromyces. The taxonomy of these fungi is not trivial, so a focus of this review has been to report the
Bladt, Tanja Thorskov +3 more
core +2 more sources
The Cultivation of Endamoeba histolytica and the in-vitro Chemotherapeutic Testing of Amebacides [PDF]
, 1952 Endamoeba histolytica is the casual organism of the disease, amebiasis. Global distribution of high incidence makes this protozoan infection an enormous public health and economic problem.
Callender, Maurice E.
core +1 more source