Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality. [PDF]
, 2018 The non-ribosomal peptide gliotoxin, which autoinduces its own biosynthesis, has potent anti-fungal activity, especially in the combined absence of the gliotoxin oxidoreductase GliT and bis-thiomethyltransferase GtmA.
Alabbadi, SH +7 more
core +2 more sources
α_νβ_3-targeted Copper Nanoparticles Incorporating an Sn 2 Lipase-Labile Fumagillin Prodrug for Photoacoustic Neovascular Imaging and Treatment [PDF]
, 2015 Photoacoustic (PA) tomography enables multiscale, multicontrast and high-resolution imaging of biological structures. In particular, contrast-enhanced PA imaging offers high-sensitivity noninvasive imaging of neovessel sprout formation and nascent ...
Allen, John S. +7 more
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Distinctive functions of methionine aminopeptidase II in embryonic haematopoiesis in zebrafish embryos [PDF]
, 2010 Oral presentationINTRODUCTION: Methionine aminopeptidase 2 (MetAP-2) is known to be the target of an anti-angiogenesis compound fumagillin and has been investigated for its robust expression in human cancers and its antiproliferative effects on ...
Chung, MIS +5 more
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Differentiation between Aspergillus flavus and Aspergillus parasiticus from Pure Culture and Aflatoxin-Contaminated Grapes Using PCR-RFLP Analysis of aflR-aflJ Intergenic Spacer [PDF]
, 2011 Aflatoxins (AFs) represent the most important single mycotoxin-related food safety problem in developed and developing countries as they have adverse effects on human and animal health. They are produced mainly by Aspergillus flavus and A.
Atoui, Ali +5 more
core +2 more sources
Washington University Record, August 11, 2006 [PDF]
, 2006 https://digitalcommons.wustl.edu/record/2077/thumbnail ...
core +1 more source
A brief account of nanoparticle contrast agents for photoacoustic imaging [PDF]
, 2013 Photoacoustic imaging (PAI) is a hybrid, nonionizing modality offering excellent spatial resolution, deep penetration, and high soft tissue contrast.
Kim, Benjamin +3 more
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Effect of Fumagillin upon Nosema apis (Zander)
Nature, 1953 A PRELIMINARY report by Katznelson and Jamieson1 on the effect of the antibiotic fumagillin (derived from an Aspergillus culture designated H–32) upon the infection of the adult honey bee by the microsporidian Nosema apis indicated promising results. They suggested that the action of the drug was prophylactic in nature, killing the infective amœboid ...
openaire +2 more sources
Drivers of genetic diversity in secondary metabolic gene clusters within a fungal species [PDF]
, 2017 Drivers of genetic diversity in secondary metabolic gene clusters within a fungal speciesFilamentous fungi produce a diverse array of secondary metabolites (SMs) critical for defense, virulence, and communication.
A Abdolrasouli +104 more
core +3 more sources
Washington University Record, April 17, 2008 [PDF]
, 2008 https://digitalcommons.wustl.edu/record/2140/thumbnail ...
core +1 more source
Development of Protacs to Target Cancer-promoting Proteins for Ubiquitination and Degradation [PDF]
, 2003 The proteome contains hundreds of proteins that in theory could be excellent therapeutic targets for the treatment of human diseases. However, many of these proteins are from functional classes that have never been validated as viable candidates for the ...
Crews, Craig M. +6 more
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