Results 111 to 120 of about 3,883,494 (274)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Online placement algorithm of service function chain based on knowledge graph

open access: yesTongxin xuebao, 2022
The emergence of new network services such as immersive cloud XR and holographic communication puts forward higher requirements for network service quality.To ensure the availability of network services, the network service delay and reliability must be ...
Zexi XU   +3 more
doaj   +2 more sources

A Method for Solving Distributed Service Allocation Problems

open access: yes, 2003
We present a method for solving service allocation problems in which a set of services must be allocated to a set of agents so as to maximize a global utility.
Vidal, Jose M
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

An energy-conscious scheduling framework for serverless edge computing in IoT

open access: yesJournal of Cloud Computing: Advances, Systems and Applications
In edge-based serverless systems, scheduling strategies that consider residual energy across the network are key to achieving efficient resource allocation for IoT devices.
Mohsen Ghorbian   +2 more
doaj   +1 more source

PENERAPAN METODE QFD (QUALITY FUNTION DEPLOYMENT) PADA HOTEL PELANGI I MALANG [PDF]

open access: yes, 2007
Keywords: QFD This research is a survey with the title "Application of QFD Method for Improving Service Quality At Rainbow Hotel I Malang". The purpose of this research is to plan for improving the quality of service at Hotel Rainbow I Malang and to ...
Dewi, Natalia Kristian
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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